Abstract Details

Title No Association Between Number of Stent Retriever Passes and Hemorrhagic Transformation for Mechanical Thrombectomy Patients.

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P1 - Poster Session 1 (5:30 PM-6:30 PM)

Poster/Presentation
Number 3-025

Objective

To assess the association, if any, that exists between the number of passes with a stent retriever and the incidence of Hemorrhagic Transformation (HT) for patients undergoing mechanical thrombectomy.

Background Previous research has primarily investigated the association between HT incidence and baseline variables (i.e. pre-procedural variables) rather than the association between HT incidence and endovascular treatment (EVT) procedural variables (e.g. the number of passes with a stent retriever). Current stent retriever guidelines recommend a maximum of 2 passes per device and not more than 3 passes per vessel.

Design/Methods Data from patients who underwent EVT with a Trevo, Solitaire, or Penumbra stent retriever from the years 2012 to 2018 was collected and categorized according to the incidence of HT. HT was defined as any intracranial hemorrhage in the territory of the initial ischemic event within admission and determined via CT scan read by radiology. Univariate and bivariate statistical analyses were conducted on the number of passes per procedure with a stent retriever, patient demographic data, patient morbidities, and patient outcomes to investigate their association with HT incidence.

Results

Of 329 total patients, 46 (14%) had HT. The HT group had an average[SD] of 1.65[0.67] and range of [1-3] passes while the non-HT group had an average[SD] of 1.63[0.86] and range of [1-5] passes per procedure. Admission NIHSS score (p = 0.0003) and the incidence of diabetes mellitus (DM) (p=0.05) were significantly higher in the HT group. Upon bivariate logistic regression, the number of passes failed to show any association with HT (p = 0.804) while admission NIHSS score was found to have an OR of 1.07 (95% CI: 1.03 - 1.12, p = 0.001) with HT incidence.

Conclusions

No significant association was found between HT incidence and the number of passes with a stent retriever. Further research investigating additional EVT procedural variables is warranted.

Authors/Disclosures
Ameer Hassan, DO (Valley Baptist Medical Center) PRESENTER	Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Medtronic. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Stryker. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Penumbra. Dr. Hassan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Cerenovus. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Viz.ai. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Genentech. Dr. Hassan has received research support from GE Healthcare.
	No disclosure on file
Umar Shariff, MD	No disclosure on file
	No disclosure on file
Wondwossen G. Tekle, MD	Dr. Tekle has nothing to disclose.
Hamza I. Maqsood, MD (Dept of Neurology)	Dr. Qureshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AstraZeneca.

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