Abstract Details

Title Impact of Race on Mechanical Thrombectomy Safety Outcomes

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P1 - Poster Session 1 (5:30 PM-6:30 PM)

Poster/Presentation
Number 3-028

Objective To describe any difference in mechanical thrombectomy (MT) safety outcome among different races.

Background The prevalence and popularity of MT in acute ischemic stroke continues to increase, however there continues to be a significant rate of complications in a certain percentage of patients. Despite known differences in ischemic stroke presentation and incidence among races it is unclear if there are also differences in MT safety outcome.

Design/Methods A retrospective analysis was performed in consecutive patients undergoing MT from 2/7/2015 to 6/29/2017 in a large tertiary care center. Data was collected by independent chart review of the electronic medical record. Multinomial logistical regression analysis was performed.

Results The cohort included 180 patients, median age 73y, 55% women. 21% were Caucasian, 45% Hispanic Caucasian, 27% African American, 7% other. Multiple metrics of safety outcomes were assessed, none of which met statistical significance. These included severe disability (Modified Rankin Score >=5 (p=0.66)), hemorrhagic conversion following procedure (p=0.39), subarachnoid hemorrhage following procedure (p=0.50), TICI score <= 2a (p=0.91), worsening NIHSS following procedure (p=0.41). Although not statistically significant, assessment of worsening NIHSS and disability showed increased OR in other races when compared to Caucasians (OR 1.35 to 2.21 in worsening NIHSS). Overall there was no difference in efficacy outcomes by race.

Conclusions There is no statistical difference between non-Hispanic Caucasians, Hispanic Caucasians, and African American with respect to safety outcomes in the sample studied. A larger multicenter analysis is needed for further analysis.

Authors/Disclosures
Nicholas Liaw, MD, PhD (VNSC) PRESENTER	No disclosure on file
Vasu Saini, MD	Dr. Saini has nothing to disclose.
Dileep R. Yavagal, MD, FAAN (University of Miami Miller School of Medicine)	Dr. Yavagal has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Vascular Dynamics. Dr. Yavagal has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Guidepoint. The institution of Dr. Yavagal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GLG. Dr. Yavagal has received personal compensation in the range of $0-$499 for serving as a Consultant for Medtronic. Dr. Yavagal has received personal compensation in the range of $0-$499 for serving as a Consultant for Cerenovus/Johnson & Johnson. Dr. Yavagal has received personal compensation in the range of $0-$499 for serving as a Consultant for Stryker. Dr. Yavagal has received personal compensation in the range of $0-$499 for serving as a Consultant for Poseydon. Dr. Yavagal has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Athersys. Dr. Yavagal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gravity Medical Technology. Dr. Yavagal has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Poseydon. Dr. Yavagal has stock in Poseydon. Dr. Yavagal has stock in Galaxy Therapeutics. Dr. Yavagal has stock in Stentrode. Dr. Yavagal has stock in Gravity Medical. Dr. Yavagal has stock in Gravity Medical Technology. Dr. Yavagal has stock in Athersys. Dr. Yavagal has stock in Rapid Medical . Dr. Yavagal has received intellectual property interests from a discovery or technology relating to health care. Dr. Yavagal has received personal compensation in the range of $5,000-$9,999 for serving as a Medicolegal Expert with Royal Carribean Cruise Line. Dr. Yavagal has received personal compensation in the range of $5,000-$9,999 for serving as a Medicolegal Consultant with Carnival Cruise Line.

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