During the study period we found 211,114 patients with CNS cancers in the United States. Overall we found significant changes in all four categories we looked at. From 2009 to 2014 mean hospital charges increased from $70,761 to $99,517 (p < .005) and mean hospital costs increased from $21,056 to $26,544 (p < .005). On a larger scale we also analyzed mean aggregate charges and mean aggregate costs. In 2009 aggregate charges were $2,312,823,603 and in 2014 reached $3,534,724,905 (p < .005). Similarly, mean aggregate costs went from $688,048,943 in 2009 to $942,404,974 (p < .005). Yearly changes were only significant in two instances mean hospital charges from 2012 to 2013 and mean aggregate costs from 2009 to 2010.