Abstract Details

Title Does CIDP Increase The Risk of Acquiring Other Autoimmune Disorders? A New York State Planning and Research Cooperation System Database Analysis (1998-2014)

Topic Autoimmune Neurology

Presentation(s) P2 - Poster Session 2 (5:30 PM-6:30 PM)

Poster/Presentation
Number 15-105

Objective To investigate the association of CIDP with other autoimmune disorders

Background

CIDP have been associated with other autoimmune disorders in a few case reports.

Design/Methods

Patients were retrieved from the Statewide Planning and Research Cooperative System (SPARCS) database for the 1998 - 2014 time period using the Principal Diagnosis Code for CIDP.

We compared the incidence of 4 autoimmune disorders (Guillain-Barré syndrome (GBS), Myasthenia Gravis (MG), Acute Disseminated Encephalomyelitis (ADEM) and Systemic Lupus Erythematosus (SLE)) in CIDP with multiple sclerosis, an autoimmune disorder, and migraine, a disorder without autoimmune component.

Results We identified 2850 , 29808 and 275631 patients with CIDP, MS and migraine respectively. The incidence of the above autoimmune disorders was significantly higher in CIDP group compared to MS and migraine groups respectively (13.1% vs 0.7% vs 0.45% p<0.0001). GBS was reported in 11.2% of CIDP, 0.11% of MS and 0.03% of migraine patients p<0.0001; MG was reported in 0.88% of CIDP, 0.21% of MS and 0.04% of migraine p<0.0001; ADEM was reported in 0.07% of CIDP 0.02% of MS and 0.0007% of migraine p=0.10; SLE was reported in 0.74% of CIDP, 0.35% of MS and 0.37% of migraine p<0.0015.

Conclusions CIDP patients are more likely to also develop other autoimmune disorders compared to patients with MS and Migraine. Work in progress to determine the temporal association between autoimmune disorder and CIDP, the role of age, gender and comorbid conditions in the occurrence of autoimmune dysfunction in CIDP.

Authors/Disclosures
Sanjila Islam, MD (Rutgers New Jersey Medical School) PRESENTER	Dr. Islam has nothing to disclose.
Anil Thatikonda	No disclosure on file
Kevin Nolasco	Kevin Nolasco has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file
Nizar Souayah, MD, FAAN (NJMS)	Dr. Souayah has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Takeda. Dr. Souayah has received publishing royalties from a publication relating to health care.

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