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Abstract Details

Differences in Presenting Symptoms of Acute Stroke Among Young and Older Adults
Cerebrovascular Disease and Interventional Neurology
P2 - Poster Session 2 (5:30 PM-6:30 PM)
3-002
To assess potential differences in stroke symptoms in young adults (ages 18-50) and older adults (ages > 50).

In the general population, there is limited awareness of stroke symptoms and limited recognition of stroke as a disease affecting all ages. Prior studies demonstrated that young adults present late to medical attention, have lower initial NIHSS, and are frequently misdiagnosed. 

This is a retrospective cohort study including patients ages 18 and older hospitalized with a diagnosis of acute ischemic stroke (AIS), transient ischemic attack (TIA), or nontraumatic intracerebral hemorrhage (ICH) between 1/2016-12/2016. Covariates included fluctuation of deficits, whether the chief complaint was a focal or non-focal neurologic symptom, and whether there was progression of deficits within 24 hours of symptom onset. Covariates were compared between young and older adults with Fisher’s exact test and Chi-square test.

252 subjects were included in this study (44 young adults, 208 older adults). The distribution of stroke subtypes was not different between young and older adults (66% versus 71% AIS, 9% vs 14% TIA, 25% vs 15% ICH, p=0.3). Overall, 13% had fluctuating deficits, 29% presented with a non-focal chief complaint, and 30% had progression of deficits. Among those with progression, 30% had gradual worsening, 16% had abrupt worsening, 45% had a worsening of initial deficits, and 65% had a new deficit. Young adults were more likely to have a progression of deficits than older adults (43% versus 27%, p=0.03). Fluctuation was similar in frequency between young and older adults (16% versus 13%, p=0.6), as was a non-focal chief complaint (26% vs 30%, p=0.6).
A large proportion of adults of all ages with stroke present with non-focal chief complaints, increasing risk for misdiagnosis. Young adults are more likely than older adults to have progression in neurologic deficits: this may be important in treatment decision making.
Authors/Disclosures
Haley Huggins, MD (Boston Medical Center)
PRESENTER
Dr. Huggins has nothing to disclose.
Lester Y. Leung, MD (Tufts Medical Center) Dr. Leung has received research support from NIH.