This is a case report of jellyfish envenomation in a 27-year old male presenting with stiffening of extremities in Laiya, Batangas, Philippines. After the sting, he developed progressive obtundation and agitation with repeated trunk flexion and stiffening of extremities. Work-up revealed that he had recurrent generalized muscle spasms from neurotoxicity secondary to the jellyfish envenomation. He was sedated with benzodiazepines and given sodium channel blockers and muscle relaxants. The patient had progressive clinical improvement after initial intensive care monitoring and was discharged ambulatory on the 17th hospital day. The usual manifestation of Jellyfish envenomation is a mild disease of local skin irritation. However, in rare instances, it may manifest as Irukandji syndrome, like in our case.