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Abstract Details

KICK-OUT PD: Mobility, Quality of Life, and Feasibility Outcomes in a Pilot Study of a PD-Specific Karate Intervention
Movement Disorders
P2 - Poster Session 2 (5:30 PM-6:30 PM)
10-015

To evaluate feasibility of a community-based karate class tailored for individuals with early- to middle-stage Parkinson’s Disease (PD); to assess effect of karate on objective and patient-reported outcomes.  

Different exercise modalities benefit PD patients. The karate program evaluated here incorporates vigorous resistance and aerobic activity with mindfulness in a community-based class of mild to moderate PD subjects.

Open label, 10-week study of twice weekly, PD-specific, non-contact karate classes for patients with Hoehn & Yahr (HY) stage 1-3. Feasibility was assessed by overall dropout rate and adherence via attendance records. Participants completed pre- and post-intervention assessments of mobility (Timed up and Go), gait (Tinetti mobility test), quality of life (PDQ-8), and global impression of change (PGIC).

We enrolled 19 participants; 15 completed all ten weeks of classes (79%), with mean adherence of 87% among completers. Reasons for withdrawal: scheduling conflicts, no given reason, pre-existing sciatica, and appendicitis. Among those completing the study, 53% were women, median age 68 (range 39-80), PD duration of 6 years (range 2-20), and 93% were HY 2. We found significant improvements in quality of life (PDQ-8: 25.3 vs. 19.3, p = 0.01), and gait (Tinetti Mobility Test: 27.1 vs. 27.9 points, p = 0.01), and a trend toward improvement in mobility (Timed Up and Go: 9.6 vs. 9.0 seconds, p = 0.1). On the PGIC, 87% endorsed feeling moderately or considerably better. All met their self-defined pre-intervention goal, planned to continue karate, and would recommend it to a friend, respectively.

 

A twice-weekly karate class was met with high adherence and enthusiasm among people with early- to middle-stage PD. After ten weeks of participation, significant improvements were noted in gait, quality of life, and self-reported impression of change. Karate for PD is a promising intervention with potential to impact quality of life and mobility.

Authors/Disclosures
Brianna J. Sennott, MD
PRESENTER
An immediate family member of Dr. Sennott has received personal compensation for serving as an employee of Abbott Laboratories.
No disclosure on file
Monica Lee No disclosure on file
No disclosure on file
Deborah H. Hall, MD, PhD, FAAN (Rush University) Dr. Hall has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for 好色先生. Dr. Hall has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier - Parkinsonism and Related Disorders. Dr. Hall has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Annals of Neurology. The institution of Dr. Hall has received research support from Parkinson's Foundation. The institution of Dr. Hall has received research support from CHDI. The institution of Dr. Hall has received research support from Uniqure. The institution of Dr. Hall has received research support from NIH.
Cynthia L. Comella, MD, FAAN (Rush University Medical Center) Dr. Comella has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Ipsen. Dr. Comella has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vima. Dr. Comella has received publishing royalties from a publication relating to health care. Dr. Comella has received publishing royalties from a publication relating to health care.
Jori Fleisher, MD, MSCE, FAAN (Rush University Parkinson's and Movement Disorders Program) The institution of Dr. Fleisher has received research support from Parkinson's Foundation. The institution of Dr. Fleisher has received research support from NIH/NINDS. The institution of Dr. Fleisher has received research support from NIH/NINDS. The institution of Dr. Fleisher has received research support from NIA/NINDS. The institution of Dr. Fleisher has received research support from NIA/NINDS. Dr. Fleisher has received publishing royalties from a publication relating to health care. Dr. Fleisher has received personal compensation in the range of $0-$499 for serving as a Speaker with Parkinson's Foundation. Dr. Fleisher has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Lewy Body Dementia Association. Dr. Fleisher has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Davis Phinney Foundation. Dr. Fleisher has a non-compensated relationship as a Editorial Board Member with AAN Brain & Life Magazine that is relevant to AAN interests or activities.