Abstract Details

Title Increased Optic Nerve Sheath Diameter after Mild Traumatic Brain Injury in a High-Risk Population

Topic Neuro Trauma, Critical Care, and Sports Neurology

Presentation(s) P2 - Poster Session 2 (5:30 PM-6:30 PM)

Poster/Presentation
Number 4-054

Objective To examine if increased optic nerve sheath diameter (ONSD) as measured by ultrasound is an indicator of mild traumatic brain injury (mTBI).

Background Diagnosis of mTBI is difficult and subjective. Currently there are no purely objective methods for detecting mTBI. Our lab has demonstrated that transient increases in intracranial pressure (ICP) can increase the ONSD as measured by ultrasound. This study examined if mTBI is correlated with increased ONSD as measured by ultrasound.

Design/Methods Mixed martial arts (MMA) and boxing participants without prior TBI were the study population in this prospective cohort study with repeated measures. Baseline ONSD measurements were obtained using the SonoSite NannoMaxx ultrasound system and an L25 linear transducer. Participants' ONSDs were measured at initial enrollment, 1 month, and 6 months. Participants were monitored for suspected mTBI via a monthly phone call and self-report. Within two weeks following a sport concussion assessment tool (SCAT2) and physician-confirmed mTBI event, a member of the research team measured the participant’s ONSD.

Results Twenty-three participants were followed for 6 months. Four participants experienced a mTBI, with a SCAT2 score between 10-100, Glasgow Coma Scale (GCS) score of 15, and no loss of consciousness reported. The ONSD was significantly increased for these four participants (mean = 5.94mm, 95% CI [5.79, 6.09]) compared to the cohort’s baseline measurements (mean = 4.92mm, 95% CI [4.40,5.44]; p = 0.0007) and their own pre-mTBI measurements (mean = 5.28mm, 95% CI [5.03,5.54]; p = 0.0242). These increases were statistically significant.

Conclusions In this pilot study, participants' ONSDs increased after an MMA-related mTBI event and were significantly greater than those of individuals without a history of TBI. These results suggest that ultrasound measurement of the ONSD could be a viable option for quickly and objectively detecting mTBI.

Authors/Disclosures
Chloe E. Super, MD (Saint Louis Children's Hospital) PRESENTER	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file

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