Abstract Details

Title Association of rhythmic and periodic EEG patterns in ICU patients and in-hospital mortality

Topic Neuro Trauma, Critical Care, and Sports Neurology

Presentation(s) P2 - Poster Session 2 (5:30 PM-6:30 PM)

Poster/Presentation
Number 4-081

Objective

Exploring the association between rhythmic and periodic EEG patterns and in-hospital mortality by using EEG as a biomarker of acute brain dysfunction in ICU and determing if abnormal brain wave patterns on EEG make a difference in quality of care

Background

Abnormal brain wave patterns can only be detected by using EEG, so it becomes necessary to determine whether specific abnormal brainwave patterns detected by EEG in the ICU setting make a difference in outcome and quality of patient care. Increased use of routine and long term EEG’s has led to recognition of adverse brain wave patterns in comatose patients and the ACNS has developed a standardized terminology for reporting EEG performed in the ICU setting

Design/Methods

Retrospective cross sectional design, a total of 2,084 ICU EEGs were identified for a 2 yr period. EEGs were reviewed using the ACNS standard ICU EEG terminology. The primary endpoint was in-hospital mortality and secondary endpoints were length of stay and discharge disposition, the two comparison groups were patients that had EEGs with rhythmic delta activity or periodic discharges versus those without abormal patterns during the ICU stay

Results Total 2,082 EEGs were performed corresponding to 1,376 pt visits, 129 EEGs were not found in the database and 136 were excluded due unavailable medical records, a total of 1817 EEGs were reviewed corresponding to 1237 pt encounters. Primary endpoint showed abnormal discharges in 194/1237 (15.6%)pts, total number of pts died 285/1237 (23.0%), in hospital deaths in exposed group 82/194 (42.2%), in hospital death in unexposed group 203/1034 (19.6%), odds of death in exposed group 82/112 (0.732), odds of death in unexposed group 203/831 (0.244), odds ratio of 2.93 (95% CI 2.12 - 4.05, P<0.0001)

Conclusions

Patients with rhythmic or periodic patterns but not electrographic seizures have increased odds of in-hospital mortality of 2.93 (95% CI 2.12 - 4.05, P<0.0001)

Authors/Disclosures
Carlos F. Muniz, MD (SUNY Upstate Medical University) PRESENTER	Dr. Muniz has received intellectual property interests from a discovery or technology relating to health care.
Mohammad K. Ali, MD	No disclosure on file
Andrea S. Synowiec, DO, FAAN (Allegheny Health Network)	Dr. Synowiec has received personal compensation in the range of $50,000-$99,999 for serving on a Speakers Bureau for Amgen. Dr. Synowiec has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Lilly. Dr. Synowiec has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Allergan. Dr. Synowiec has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Biohaven.
Kevin M. Kelly, MD, PhD	Dr. Kelly has nothing to disclose.

��ɫ��

��ɫ��