Abstract Details

Title Incidence of Pregnancy Related Migraine Headache During Pregnancy and Post-Partum and Associated Comorbidities: An Update from a Nationwide Inpatient Sample Database

Topic Headache

Presentation(s) P3 - Poster Session 3 (5:30 PM-6:30 PM)

Poster/Presentation
Number 13-008

Objective

To review the association of migraine in pregnancy and the post-partum period and to review the frequency of associated comorbidities in this population.

Background Migraine disproportionately effects women of child bearing age. Previous studies have shown that the frequency of migraine headaches decreases during pregnancy. However, migraine during pregnancy may be associated with higher morbidity and mortality. Incidence of hospitalization for migraine in pregnancy and the incidence of comorbid conditions may further increase awareness of these associations and improve patient outcomes.

Design/Methods The Nationwide Inpatient Sample (NIS) database was utilized from years 2005-2014, and the International Classification of Disease-Ninth Revision (ICD-9) was used to identify admission for migraine during pregnancy and post-partum. Additionally, we looked at associated comorbid conditions during pregnancy in patients with migraine. Associations were generated by Cochrane-Armitage test for categorical variables and simple linear regression for continuous variables.

Results A total of 43,437,621 pregnancy related hospitalizations and 269,191 cases of Migraine (99% ante-partum and 1% post-partum) were noted during the study period. The incidence of hospitalization for migraine during the study period was 620 per 100,000 pregnancies. Hospitalization for migraine during pregnancy was a predictor of increased incidence of preeclampsia (OR:2.05, 95% CI:1.96-2.15, p<0.001), preterm delivery (OR:1.14, 95% CI:1.11-1.17, p<0.001) and stroke (OR:13.1, 95% CI:6.53-26.12, p<0.001).

Conclusions Rates of admission to the hospital for migraine were less during pregnancy than the post-partum period. Hospitalization for migraine during pregnancy is associated with more comorbidities such as preeclampsia, stroke, and preterm delivery. Identification and better management of migraine in this population may help identify and potentially treat these comorbidities.

Authors/Disclosures
Martin A. Myers, MD (James A Haley VA) PRESENTER	No disclosure on file
Charles W. Brock, MD	No disclosure on file
Chirag N. Savani, MD (Tampa General Hospital)	No disclosure on file
	No disclosure on file

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