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Abstract Details

Left hemispatial neglect with a splenial lesion
Aging, Dementia, and Behavioral Neurology
P3 - Poster Session 3 (5:30 PM-6:30 PM)
9-023
The goal of this report is to learn the role of the splenium of the corpus callosum in mediating visuospatial attention.
With injury of the anterior two thirds of the corpus callosum, each hemisphere’s attentional bias to contralateral hemispace becomes manifest with each hand deviating ipsilaterally during line bisection tasks. Patients with infarctions in the right posterior cerebral artery distribution with occipital and splenial damage can also exhibit spatial neglect. 
A right-handed woman with Marchiafava-Bignami disease and damage to the splenium of her corpus callosum without evidence of a mesial frontal, parietal, or occipital injury was assessed for spatial neglect with line bisections. 
When bisecting lines in her left hemispace with her right hand, she deviated to the right, but revealed no major deviations when the line was place in the midline, in right hemispace, or when bisecting lines with her left hand.

This patient provides evidence that damage to the splenium can induce a special form of asymmetrical spatial neglect. This asymmetry might be related to the disconnected right hemisphere’s ability to allocate attention to both right and left hemispaces with the disconnected left hemisphere’s ability to allocate attention to the right but not left hemispace.

Authors/Disclosures
Tigran Kesayan, MD (VUMC Pain Medicine and Neurology)
PRESENTER
Dr. Kesayan has nothing to disclose.
No disclosure on file
Kenneth M. Heilman, MD, FAAN (Univ. of Florida, Dept. of Neurology) Dr. Heilman has received publishing royalties from a publication relating to health care.