We identified total weighted ischemic stroke 3.5M from 2007 to 2014. From them, 1.7M (48.1%) were admitted to teaching and 1.8M (51.9%) to non-teaching hospital. Compared to nonteaching, teaching hospitals administered more tPA 6.34% vs. 3.86% (P value <0.0001), performed more mechanical thrombectomy (MT) 0.76% vs. 0.09% (p <0.0001). However, teaching hospitals also had higher post-tPA ICH 0.51% vs. 0.26 (p <0.0001) and post-MT ICH 0.13% vs. 0.02% (p <0.0001). Mortality rate was 5.12% vs. 4.70% (p=0.0095), cost was $13,713 vs. $10,459 (p <.0001) and LOS was ≈5.6 vs. ≈4.7 days (p <0.0001) at teaching hospitals. After adjusting multivariables, teaching hospitals were found to have a higher odds of ICH with advanced age 1.007 (p <0.0001), tPA use 3.216 (p <0.0001), MT 7.555 (p <0.0001), charlson comorbidity index 1.109 (p <0.0001), alcohol abuse 1.206 (p 0.0001), while history of well-controlled hypertension 0.897 (p <.0001) and female sex 0.856 (p <.0001) reduced the odds of ICH.