Abstract Details

Title A Task-Based Approach to Quantifying Movement Deficits Due to Stroke

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P3 - Poster Session 3 (5:30 PM-6:30 PM)

Poster/Presentation
Number 3-048

Objective

To quantify movement deficits of a right hemisphere stroke.

Background There is currently no effective solution for quantifying the impact of stroke on limb movement. Current clinical assessments, while useful, are crude and often unable to discern subtle changes and deficits.

Design/Methods We studied 6 normal subjects (5 female, ages 29-51 years, all right-hand dominant), and 5 patients who had recently suffered a right hemisphere stroke (3 female, ages 47-86, 3 right and 2 left hand dominant). The subjects wore a 3-axis accelerometer on the left and right hands, and performed tasks, consisting of specific motions, for the purposes of obtaining standardized data.

Results The patients all had left side weakness. The NIHSS was 11, 9, 1, 5, and 2. Left arm strength was 0/5, 0/5, 4/5, 4/5, and 4/5 and right arm strength was 4/5, 5/5, 5/5, 5/5, and 5/5. Acceleration in the X, Y and Z axes during the tasks were sampled and analyzed. The average absolute acceleration values were determined during a selected task for each of the 6 normal subjects and 5 stroke patients. A linear classifier was constructed to classify stroke and normal subjects based on the average acceleration for the left and right arms. The separability of stroke and normal subjects was tested with the leave-one-out (LOO) approach. We achieved perfect separation of stroke and normal subjects with all eleven LOO tests, underscoring the robustness of the quantification of the limb movement in normal and stroke subjects.

Conclusions

It is possible to quantify the impact of a right hemisphere stroke using simple movement tasks and multiple 3-axis accelerometers. Our results provide the basis for quantifying the impact of stroke.

Authors/Disclosures
Bradley Cahn PRESENTER	Mr. Cahn has nothing to disclose.
Jill T. Shah	No disclosure on file
	No disclosure on file
Cora Ormseth	No disclosure on file
Hitten Zaveri	No disclosure on file
Kevin N. Sheth, MD, FAAN (Yale UniversityDivision of Neuro and Critical Care)	Dr. Sheth has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ceribell. Dr. Sheth has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Zoll. Dr. Sheth has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for NControl. Dr. Sheth has received stock or an ownership interest from Astrocyte. Dr. Sheth has received stock or an ownership interest from Alva. The institution of Dr. Sheth has received research support from Biogen. The institution of Dr. Sheth has received research support from Novartis. The institution of Dr. Sheth has received research support from Bard. The institution of Dr. Sheth has received research support from Hyperfine. Dr. Sheth has received intellectual property interests from a discovery or technology relating to health care.

��ɫ��

��ɫ��