Thyrotoxic Periodic Paralysis (TPP) is a condition of reversible paralysis associated with severe hypokalemia secondary to hyperthyroidism. It is most commonly seen in Asian men, although thyroid disease is more common in women. The disease process is primarily mediated by thyroid hormone, but exacerbated by insulin and agonist stimulation of the beta-adrenergic receptors. The pathophysiology is associated with over-activation of the Na+-K+-ATPase and subsequent hyperpolarization. Resultant electrolyte abnormalities can lead to transient paralysis, renal failure, and cardiac arrhythmia/cardiac arrest. Immediate pharmacological therapy with beta-blockers, thyroid medication, and potassium replacement reduce morbidity and mortality. We present a case of a 32-year-old Hispanic male with medical history of alcoholism and stimulant abuse who presented to the hospital due to bilateral, proximal, lower extremity weakness that began two days prior. Symptoms progressed with acute worsening after a meal with heavy carbohydrate load on the day of admission.