Abstract Details

Title Influence Of Early Neurological Complications On Clinical Outcome Following Heart Transplantation.

Topic General Neurology

Presentation(s) P3 - Poster Session 3 (5:30 PM-6:30 PM)

Poster/Presentation
Number 4-069

Objective The aim of our study is to evaluate the impact of neurological complications on the outcome of patients with heart transplantation.

Background Neurological complications in orthotopic heart transplantation represent a major cause of morbidity and mortality despite successful transplantation.

Design/Methods We retrospectively studied 193 patients who underwent heart trasplant at Hospital Italiano in Buenos Aires from November 2014 to August 2018. We evaluated demographic and clinical variables and outcome of patients with and without neurological complications.

Results We included 193 patients with a mean age of 51±12 years of which 74% (n=143) were men. The two most frequent causes that led to heart transplantation were idiopathic in 34% (n=65) and ischemic in 29% (n=56) of the cases. In 91% (n=175) of the cases the transplant was urgent due to heart failure and hemodynamic instability was present at the moment of transplant in 92% (n=176) of the cases. Central neurological complications in the first week post-transplant occurred in 12% (n=23) of the patients. The most frequent were: encephalopathy (5%), subdural hematoma (2%), subarachnoid hemorrhage (2%), seizures (2%) and ischemic stroke (1%). Peripheral neuropathy was observed in 4% of cases. Hospital mortality was 11% (n=22) and 88% (n=170) was discharged at home. Central neurological complications were more frequent in those who died during hospitalization (32% vs. 9%, p=0.002).

Conclusions Perioperative neurologic complications are frequent in heart transplant recipients. Central neurological complications were associated with higher in-hospital mortality.

Authors/Disclosures
Agustin Pappolla, MD (Hospital Italiano De Buenos Aires) PRESENTER	Dr. Pappolla has nothing to disclose.
	No disclosure on file
	No disclosure on file
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	No disclosure on file
	No disclosure on file
Maria Zurru	No disclosure on file

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