To examine the relationship between employment status (no employment, part-time employment, and full-time employment) and clinical and cognitive variables; to analyze the relationships between both negative events and clinical and cognitive variables, as well as accommodations and clinical and cognitive variables.

89 MS patients (95.2% RR, 1.2% SP, 3.6% PP) were included. 66% female; mean age: 39.51±10.00 years; mean education: 14,20±2.92 years; EDSS: 2.56±1.90; disease evolution: 10.03±7.23. fatigue: 4.13±1.76; depression: 13.34±10.56

Outcomes measures: Argentina adaptation of the BVMS, EDSS, BDI II, Fatigue Scale. Cognitive outcomes: Brief International Cognitive Assessment for MS (BICAMS) (SDMT-CVLT-BVMTR); 7/24 Visuospatial Scale, PASAT 2”-3” and Verbal fluency.

18.75% are unemployed and 81.25% employees, of which 36.05% are full-time employees. ºÃÉ«ÏÈÉú (p= .026), Cognitive factor (p= .007), SDMT (p= .009), BVMTR (p= .003), Pasat3 (p= .026), Pasat2 (p= .008), 7/24 and Visuospatial Scale (p= .007), differentiate the unemployed patients from the employed patients. EDSS (p= .002), disease evolution (p= .003) and depression (p= .022) differentiate between employees full time and part time.

Depression (p=.044), Fatigue (p=.017), Clinical Factor (p=.005), Verbal Fluency (p=.016), Pasat3 (p=.004) and Pasat2 (p=.008) differentiate patients with and without negative events. Cognitive factor (p=.035), BVMTR (p=.029) and 7/24 Visuospatial (p=.039) difference patients who make accommodations in their employment.

Cognitive factors differentiate between employed and non-employed patients, while physical disability, disease evolution and depression differentiate between full-time and part-time patients. The Argentina adaptation of the BVMS is a useful tool to monitor the difficulties that patients present in their jobs.