During trekking from Ghandruk to Annapurna Base Camp, fifty-two participants were selected between 2017 October 24 and 2017 October 30, which was also during the occasion of Stroke week. Participants included were: 12 Trekking Guides, 26 National or Foreign Trekkers and 14 local people. Questionnaires in English or Nepalese language were used to assess their knowledge of stroke and its management.

Twenty-six Trekkers (100%), 8 trekking guides (66.7%) and 5 local people (35.7%) were fully or partially able to explain the meaning of stroke. Out of 9 listed symptoms, all the trekkers were able to mark minimum of 7 symptoms, half of the trekking guides were able to mark more than 5 stroke symptoms, and half of the local people were only able to mark more than 3 symptoms. All of the trekkers and trekking guides, and 4 (33.3%) local people were willing to immediately transfer stroke patient to hospital or call doctor or health worker for further treatment. Out of remaining 10 local people, 6 responded that stroke patient should be taken to faith-healer and 4 replied they could still be waited few hours to days at home to see the recovery. Out of 52 participants, only 2 foreign trekkers have heard about thrombolytic treatment, and none of them were aware of the thrombolysis time window.

Most of the local people in the hilly areas of Nepal lack the knowledge about stroke and are not well aware of early management of stroke. Unable or delay in stroke recognition can cause the higher mortality and morbidity of stroke patients.