Abstract Details

Title Correlation of Indicators of P300 Cognitive Potentials with Epilepsy Forms

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P4 - Poster Session 4 (5:30 PM-6:30 PM)

Poster/Presentation
Number 6-021

Objective To study the indices of cognitive potentials P 300 for various forms of epilepsy (symptomatic and idiopathic)

Background Event-related potentials are a useful method for assessing cognitive function, diagnosis, and effects of treatment in patients not only with psychogenic disorders but also with epilepsy. An event-related potential (ERP) is a measured brain response that is the direct result of a specific sensory, cognitive, or motor event. ERPs are measured by electroencephalogram (EEG) and represent any stereotyped electrophysiological response to a stimulus

Design/Methods The study involved data from a survey of 72 patients with epilepsy. Patients are divided into 2 groups depending on the form of the disease: Group I - 38 patients with symptomatic epilepsy (SE) and Group II - 34 patients with idiopathic epilepsy (IE). The control group consisted of 10 practically healthy persons, comparable in age. The study of the acoustic cognitive evoked potential (ACVP) or P300 was performed using the standard odd-ball paradigm technique

Results With the help of the obtained results, it was possible to identify variations in the severity and qualitative characteristics that are not homogeneous. Light emotional, disregulatory disorders, reflecting the dysfunction of cortical-subcortical structures, were revealed in FE. This manifested itself in the absence of a distinct interhemispheric asymmetry of the P300 amplitude. In patients with IE, more significant disorders were observed, characterized by the absence of interhemispheric asymmetry in the P300 amplitude and a significant increase in the P300 latency period

Conclusions

Thus, in patients with epilepsy, the neurophysiological indices of cognitive evoked potentials objectively reflect the state of higher cerebral functions in epilepsy. In idiopathic and symptomatic forms, there was no interhemispheric asymmetry of the amplitude of the P300 wave, which indicates dysfunctional disorders. The parameters of the latent period P300 are increased with symptomatic epilepsy, in contrast to idiopathic, and reflect the slowing of cognitive processes

Authors/Disclosures
Marufjon Salokhiddinov, MD (Tashkent Medical Academy) PRESENTER	No disclosure on file
	No disclosure on file

��ɫ��

��ɫ��