好色先生

好色先生

Explore the latest content from across our publications

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

Features of episodic cluster headache in the real world setting: clinical characteristics from a large, multi-national, cross-sectional survey
Headache
P5 - Poster Session 5 (5:30 PM-6:30 PM)
13-011
To describe the clinical characteristics associated with episodic cluster headache.
Cluster headache (CH) is a primary headache disorder composed of recurrent intense, unilateral headache “attacks” with associated cranial autonomic symptoms and/or restlessness.  Characterization of episodic CH patients in the real world remains limited.
Data were drawn from the Adelphi 2017 CH Disease Specific Programme, a cross sectional survey including physicians from Germany, UK and US and their consulting CH patients. Patients with episodic CH were segmented into those experiencing ≤1 (n=388), >1-≤2 (n=175), >2-≤3 (n=112) and >3 (n=201) attacks per day (APD), on average, and were analyzed descriptively.

The majority of patients were male (67%) and the mean age was 40.9 years. The proportion who smoke increased as APD increased (27% ≤1 up to 33% >3) and patients with comorbid depression almost doubled (11% ≤1 to 20% >3 APD).  Patients experienced a mean of 2.6 cluster periods per year which lasted an average of 30.8 days with a mean of 2.4 APD.  Three in ten patients had their CH condition misdiagnosed at least once prior to a confirmed CH diagnosis, most commonly being mislabelled with migraine (70%) or tension headache (22%). Most frequent current symptoms were unilateral pain (69%), orbital pain (46%), lacrimation (46%), conjunctival injection (43%) and temporal pain (41%). Symptoms were similar vs. APD. Patients reported feelings of stress (46%), anxiety (45%) and agitation (45%) being most prevalent during a typical attack, which increased proportionally as APD increased, and 67% described the level of pain suffered during a typical CH attack as severe to very severe. Reported findings were generally consistent across geographies.

Patients with episodic CH experience multiple bouts per year marked by frequent, painful attacks and a constellation of distressing symptoms.
Authors/Disclosures
James Martinez
PRESENTER
No disclosure on file
J S. Andrews J Scott Andrews has received personal compensation for serving as an employee of Eli Lilly & Company. J Scott Andrews has received stock or an ownership interest from Eli Lilly & Company.
James Jackson (Adelphi Real World) James Jackson has nothing to disclose.
Russell Nichols Russell Nichols has received personal compensation for serving as an employee of Eli Lilly and Company. Russell Nichols has received stock or an ownership interest from Eli Lilly and Company.
Sarah Cotton Sarah Cotton has nothing to disclose.
Antje Tockhorn-Heidenreich Antje Tockhorn-Heidenreich has received personal compensation for serving as an employee of Eli Lilly and Company. An immediate family member of Antje Tockhorn-Heidenreich has received personal compensation for serving as an employee of Evidera. Antje Tockhorn-Heidenreich has received stock or an ownership interest from Eli Lilly and Company . An immediate family member of Antje Tockhorn-Heidenreich has received stock or an ownership interest from PPD.
No disclosure on file
No disclosure on file