Abstract Details

Title Is there a relationship between Incidental Learning and Self-temporal Projection in relapsing remitting multiple sclerosis patients?

Topic Multiple Sclerosis

Presentation(s) P5 - Poster Session 5 (5:30 PM-6:30 PM)

Poster/Presentation
Number 15-054

Objective The aim to this study is to assess the performance on incidental learning and self-temporal projection in RMMS patients and describe the relationship between both constructs.

Background

Cognitive impairment is a frequent feature in relapsing-remitting multiple sclerosis (RMMS), which generally affects attention, memory, executive functions and processing speed with prevalence rates ranging from 40 to 65%. This cognitive impairment has a high impact in activities of daily living.

Incidental learning (IL) refers to the ability of learning new information without having the intention to do so. This type of implicit learning requires other cognitive functions such as executive functions. Even more, it requires the ability to adjust the self-temporal projection (STP) relative to their experiences and feedback implicit learning, improving its efficiency. From a clinical standpoint, there are numerous functional benefits of self-temporal projection.

Recent clinical investigations evidenced impaired IL and STP abilities in RMMS patients.

Design/Methods A complete neuropsychological test battery was performed on 23 RMMS patients and 19 healthy controls. This battery included the Digit Symbol Substitution Test (WAIS III) (incidental learning), the Rey-Osterrieth Complex Figure Test (ROCF) (incidental learning) and Self-temporal Projection test.

Results Significant differences were found in the performance on digit symbol substitution test (incidental learning) (t (36,081) = -3,035, p < .01) and the Rey-Osterrieth Complex Figure Test (incidental learning) (t (40) = -3,290, p < .01) between RMMS patients and controls. Significant differences between groups were found in the performance on future STP, but not on past STP. Positive correlations were observed on the incidental learning test (ROCF) and past and future STP.

Conclusions Incidental learning is impaired in RMMS patients and has a relation with self-temporal projection. These results are important to understand these patients’ cognitive profile in a clinical setting, especially in a rehabilitation context.

Authors/Disclosures
PRESENTER	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Vladimiro Sinay, MD	No disclosure on file
	No disclosure on file
	No disclosure on file

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