Abstract Details

Title Cerebral Venous Thrombosis In A Single Center Tertiary Hospital Of A South East Asian Country (CVSTS Study) – A Retrospective Study On The Clinical Profiles Of Patients with Cerebral Venous Thrombosis

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P5 - Poster Session 5 (5:30 PM-6:30 PM)

Poster/Presentation
Number 3-011

Objective This study aims to describe the clinical profile of Filipino patients with CVST and its management and outcome and compare it with other races/ethnicity. This would present new data to guide Filipino doctors on the extent of diagnostics and management to optimize the cost of healthcare.

Background Cerebral venous sinus thrombosis (CVST) accounts for <1% of all strokes and among the young. Large population epidemiological studies on CVST are few owing to the rarity of the disease and these are representative of the Western population. There is paucity of Southeast Asian data. In the Philippines, the work up and management is limited by cost.

Design/Methods This was a retrospective cohort of Filipino patients with CVST admitted in a tertiary hospital from 2013–2018. All patients ≥18 years old and diagnosed with CVST confirmed by neuroimaging were included. Those with imaging not indicative of CVST were excluded. Demographic and clinical data were obtained through medical records review.

Results A total of 31 patients were identified. Majority were <50 years old (n=17;54.84%) with a median age of 43 years, and with slightly more females (n=16). Thrombophilia (n=14;45.16%) is the most common predisposing factor followed by high estrogen states (n=10;62.5%) seen exclusively in females. Headaches were the most common initial complaint (n=21;67.74%) and seizures were the most common reason for admission (n=11;35.48%). Majority had no neurologic deficits (n=15, 48.39%). Thrombosis was seen in all patients and the superior sagittal sinus is most commonly involved (n=14, 45.16%). The treatment was anticoagulation (n=24, 77.42%) and antiepileptics were given only to those who presented with seizures (n=16, 51.61%). Patients were discharged with a good prognosis at MRS 0-2 (n=24;77.42%).

Conclusions

The findings are comparable with investigations done in other Caucasian, Middle Eastern, and East Asian studies. This is the first systematic data on CVST in the Philippines and Southeast Asia.

Authors/Disclosures
Miguela Marie A. Senga, MD (The Medical City) PRESENTER	Dr. Senga has nothing to disclose.
	No disclosure on file

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