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Abstract Details

Hemoglobin A1c in Intracerebral Hemorrhage: A Cross-sectional Analysis of a Large National Database.
Cerebrovascular Disease and Interventional Neurology
P5 - Poster Session 5 (5:30 PM-6:30 PM)
3-043
The current study aims to assess mean HbA1c levels in patients presenting with ICH with focus on different race/ ethnicities among the US population.

Long-term hyperglycemia contributes to the cerebrovascular disease process and is considered a risk factor for the development of ischemic stroke. Studies on intracerebral hemorrhage (ICH) have shown intra-hospital hyperglycemia to be associated with poor outcome, though no evidence exists to correlate baseline hyperglycemia as a risk factor for ICH. 
Data was collected using the Cerner Health Facts database for the years 2000-2016. Ischemic and hemorrhagic stroke was identified using the International Classification of Diseases (ICD)-9/10 codes. Hemoglobin A1C levels were extracted for all the subjects for multiple encounters. All the values for each subject were aggregated and the final mean values were taken for different race/ ethnicities. The definition of pre-diabetes for this study was 5.7%-6.4% while A1C of 6.5% or more were considered diabetes. 

A total of 625,768 patients with stroke were identified. Among these hemoglobin A1c levels of 156,380 patients were obtained. Out of these 137,061 were of Ischemic stroke (IS) and 19,319 were of Intra-cerebral hemorrhage (ICH). The mean hemoglobin A1c level was 6.8% for IS and 6.7% for ICH. In the ICH group, Caucasians and Hispanics had mean A1C levels minimally more than other races. Comparing to IS, ICH patients had similar A1C mean values.
This descriptive review of a large national database comprising of approximately 19000 ICH patients, reveals a high disease burden of pre-diabetes and diabetes mellitus in this critically ill population. Our group plans to do adjustment analysis for patients with normal A1C, pre-diabetes, and diabetes mellitus at the time of presentation with ICH and its correlation to long-term mortality.   
Authors/Disclosures
Mudassir Farooqui, MD
PRESENTER 		Dr. Farooqui has nothing to disclose.
Asad Ikram, MD, MBBS Dr. Ikram has nothing to disclose.
Owen T. Owens, DO (Intermountain Healthcare) Dr. Owens has nothing to disclose.
Sajid Suriya, MD Dr. Suriya has nothing to disclose.
Alexis Alvarado Arias, MD (University of Mississippi) Dr. Alvarado Arias has nothing to disclose.
Mohammad Abbas, MD (Lakeview Healthcare System) No disclosure on file
Andrew Lin, MD No disclosure on file
Atif Zafar, MD (St. Michael's Hospital (University of Toronto)) Dr. Zafar has nothing to disclose.