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Abstract Details

Validation of ICH and ICH-GS scores in cohort of Indian patients with Intracerebral hemorrhage
Cerebrovascular Disease and Interventional Neurology
P5 - Poster Session 5 (5:30 PM-6:30 PM)
3-045

To validate the ICH and ICH-GS scores in cohort of Indian patients with intra cerebral hemorrhage for 30 day mortality and 3 month functional outcome.

Intracerebral hemorrhage (ICH) is a devastating sub type of stroke. Various prognostic scores have been developed for prediction of mortality and functional outcome post-ICH.
This was an ambispective observational study of primary ICH cases enrolled from January 2014 till April 2018. Retrospective patients were enrolled from January 2014 till February 2017. Prospective cases were enrolled from March 2017 till April 2018 and were followed up in OPD/ telephonically for mRS at 30 day and 90 day.

A total of 617 patients, (464 retrospective and 153 prospective) of ICH were included. In hospital mortality and 30-day mortality was 28.7% and 23.2% respectively. Statistically significant (P value < 0.001) association of increasing mortality with increasing ICH and ICH GS score values was observed. Area under Receiver Operating Characteristic (ROC) curve was 78.3% and 74.4% for ICH and ICH-GS scores respectively. However mortality observed at individual scores was less than reported indicating that though the increasing scores are associated with increasing mortality, the prediction of mortality at individual ICH and ICH-GS score values may not be valid.

There was increase in poor functional outcome with increasing level of ICH and ICH-GS scores. Area under ROC curve was 86.9% and 87.9% for ICH and ICH-GS scores respectively, indicating good discriminating ability of both the scores. The AUC analysis in surgically intervened patients revealed that outcome discrimination of ICH and ICH-GS scores was negatively affected by surgical intervention. 
Both ICH and ICH-GS scores are valid in Indian population and can be effectively used for prognostication in ICH patients. However with advancing medical and surgical knowledge there is need for development of a new prognostic scale taking surgical intervention into consideration.
Authors/Disclosures

PRESENTER
No disclosure on file
Rohit Bhatia, MD, MBBS, DM Dr. Bhatia has nothing to disclose.
Deepa Dash, MD, DM Dr. Dash has nothing to disclose.
Manjari Tripathi, MD (ALL INDIA INSTITUTE OF MEDICAL SCIENCES) Dr. Tripathi has nothing to disclose.
No disclosure on file