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Abstract Details

Repetitive Transcranial Magnetic Stimulation in Improving Lower Extremity Function and Gait Among Stroke Patients: A Meta-analysis
Neuro-rehabilitation
P5 - Poster Session 5 (5:30 PM-6:30 PM)
7-005
This meta-analysis aims to determine the efficacy of supplementing Repetitive Transcranial Magnetic Stimulation (TMS) to conventional rehabilitation in facilitating improvement of lower extremity (LE) function and gait recovery among post-stroke patients.
Repetitive transcranial magnetic stimulation (rTMS) has been shown to facilitate neuroplasticity and recovery post-stroke.
Literature search was done using PubMed, Cochrane Library and GoogleScholar with keywords repetitive transcranial magnetic stimulation and lower extremity function and gait and stroke. Four randomized placebo-controlled trials were included in the meta-analysis and appraised by three independent reviewers. Review Manager was used to construct Forest plots.
Motor evoked potential amplitude (88.43 [19.05, 157.82]) and latencies (-1.49 [-2.17, -0.81]) in the tibialis anterior muscles significantly favored the rTMS group. Timed Up and Go test scores decreased significantly, 2.72 [2.22 to 3.22] seconds more in rTMS than in control groups. The change in Fugl Meyer Assessment Lower Extremity (FMA-LE) score in rTMS groups was 1.89 [-0.08 to 3.85] points higher, but not significant. The change in walking speed and cadence in rTMS groups was 2.45 cm/sec higher and 1.20 steps/min more than control, although not significant.

Overall, among post-stroke patients, rTMS is beneficial as a supplement to conventional rehabilitation in facilitating motor recovery of lower extremities. However, this may not translate to gait improvement. Further studies with larger sample size, focusing on specific rTMS parameters (frequency, duration and timing) are necessary in order establish a treatment protocol for practice.


Authors/Disclosures
Alexandria E. Matic, MD (Institute for Neurosciences St. Luke'S Medical Center-Quezon City)
PRESENTER
No disclosure on file
Jeryl Ritzi yu No disclosure on file
No disclosure on file
No disclosure on file