The current study was undertaken to determine if an online case-based medical education activity could improve the ability to recognize and effectively manage LID in patients with PD.

The intervention comprised 2 patient case scenarios in an online, interactive, text-based CME activity. Using a “test and teach” methodology, clinicians were presented with multiple-choice questions to test their application of evidence-based recommendations. Each response was followed by education in the form of detailed, referenced feedback. A paired 2-tailed t-test evaluated differences in pre- and post-assessment answer choices and McNemar’s test measured changes in paired responses to individual questions. Cramer’s V was used to calculate the effect size of the intervention. Data from the educational intervention were collected between June 15, 2018 and July 24, 2018.

Comparison of responses to questions before and after education demonstrated statistically significant improvements and an extensive educational effect for neurologists (n=110; P <.001; V =.342). Significant increases in knowledge and competence were observed in several specific areas (P <.05 for all comparisons): recognition of clinical symptoms indicative of LID; selection of amantadine as therapy for LID after levodopa dose adjustment; and differentiation of the available formulations of amantadine. Participation in this activity resulted in 35% of neurologists reporting an improvement in confidence to identify the clinical value of different amantadine formulations for the management of LID.