Abstract Details

Title Effect of seizures on outcomes in patient with cardiac surgery

Topic Neuro Trauma, Critical Care, and Sports Neurology

Presentation(s) P14 - Poster Session 14 (8:00 AM-9:00 AM)

Poster/Presentation
Number 13-008

Objective

To study the effect of acute seizures on post-operative outcomes in patients undergoing cardiac surgery (CS).

Background Acute seizures and status epilepticus can occur after acute brain injury. Postoperative seizures can occur in patients after CS. Seizures in CS patients can be caused by stroke, drug reaction, fever, or metabolic derangement. There is limited literature on risk factors for postoperative seizures after CS. We examined the incidence of seizures from a population of adult patients who underwent CS at a major tertiary center.

Design/Methods We performed a retrospective chart review of patients admitted to our center from September 2015 to August 2018. We identified 14 patients with definite seizures. Patients with possible seizures, history of epilepsy and nonepileptic events were excluded. Patient demographics, risk factor profile, EEG and imaging studies, laboratory data, seizure characteristics and length of stay (LOS) were obtained from chart review. We also compared the seizure group with the non-seizure group.

Results

Seizures occurred in 14 of the 3392 patients (0.4%) with CS. Table 1 shows demographic and clinical data. The mean age (in years) was 61 and 55 respectively. There were 10 females (71%) in the seizure group and 1248 (37%) in the non-seizure group. The mean left ventricular ejection fraction was 58 Vs 55 (p = 0.74). The average LOS was 11 days for the seizure group and 5 days for non-seizure group (p<0.01). Less than half of patients in the seizure group (46%) compared to 76% of patients in non-seizure group were discharged home (p = 0.01). One patient in the seizure group (7%) whereas 117 (3%) in the non-seizure group died (p = 0.75).

Conclusions

Acute seizures are uncommon neurological complication in patients undergoing CS. Seizures in CS patients are associated with prolonged hospital LOS and prolonged post-operative rehabilitation but not significantly associated with early post-operative mortality.

Authors/Disclosures
Vishwanath Sagi, MD, FAAN (University of Louisville, Department of Neurology) PRESENTER	Dr. Sagi has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file

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