The objective of the present study was to accurately determine the prevalence and association factors of obstructive sleep apnea (OSA) in unselected adult patients with epilepsy (PE).

We conducted a cross-sectional study of consecutive subjects more than 15-year-old without known sleep disorders or prior PSG were recruited from a secondary care, tertiary care and university hospital. Participants underwent polysomnography. Scoring was performed by 2 blinded board-certified sleep physician and senior sleep technologist.

We invited 178 patients with unknown cause of epilepsy from our clinic. One hundred sixty-eight were participate in our study. The PE main characteristics: 78 men/ 59 women, mean age= 35.9, SD= 13.9, range 16 - 76. Mean RDI of our populations was 8.8 (range 0-82.2. thirty-one (18.5%) patients with epilepsy were found OSA, 19 patients have mild to moderate OSA and 11 patients have severe OSA. The traditional OSA risk factors of male, age, neck circumference, snoring and Sleep Apnea Scale of the Sleep Disorders Questionnaire were predictive of OSA, without relationship with number of seizures, number of antiepileptic drugs, age of onset, duration of epilepsy, STOP-BANG in univariate analyses. OSA predictors in multivariate modeling included age, neck circumference, and snoring.