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Abstract Details

Clinical Features of LGI-1 Antibodies Positive Encephalitis with Faciobrachial Dystonic Seizures Turning to the Counterpart Side.
Autoimmune Neurology
Autoimmune Neurology Posters (7:00 AM-5:00 PM)
094

OBJECTIVE: To investigate the clinical feature of faciobrachial dystonic seizure (FBDS), which convert to the contralateral side.

BACKGROUND: FBDS were recognized as the epileptic origin. However, ictal scalp EEG is usually normal. The mechanizms of FBDS were not fully investigated.

 

DESIGN/METHODS: A 72-year-old male with right-sided FBDS due to LGI1-Ab encephalopathy. He had involuntary dystonic movement of right hands and mouth for three months before admission. His serum sodium was normal. Correlation between clinical course and findings of MRI and EEG was serially analysed.

RESULTS: On day 1, His MRI showed T1 hyperintensity of right basal ganglia and T2 hyperintensity of left basal ganglia. On day 9, right basal ganglia was enhanced. On day 10, his EEG showed rhythmic slow activities arising from right frontal region. Midazolam and corticosteroid infusion were effective to FBDS. AEDs were continued. LGI-1 Ab were positive. 5 months after onset, left FBDS was appeared. His EEG showed rhythmic fast activities arising from right frontal region.
CONCLUSIONS: The present study showed that the both type to FBDS were associated with the different EEG pattern. 
Authors/Disclosures
Hiroya Ohara, MD
PRESENTER 		Dr. Ohara has nothing to disclose.
No disclosure on file
No disclosure on file
Masako Kinoshita, MD, PhD (8 Ondoyamacho) Dr. Kinoshita has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Otsuka Pharmaceutical Co., Ltd.. Dr. Kinoshita has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eisai Co., Ltd.. Dr. Kinoshita has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for UCB Japan Co. Ltd. . Dr. Kinoshita has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Daiichi Sankyo Company, Limited.. The institution of Dr. Kinoshita has received research support from Japan Society for the Promotion of Science. The institution of Dr. Kinoshita has received research support from Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering .