The aim of the study is to analyse the various parts of corpus callosum involved in the disease processes and the etiological predilection to corpus callosum.

The commissural fibers contained in various parts such as rostrum, genu, body and splenium of corpus callosum are affected by various disease process. It is commonly affected in various acquired disease process, the pattern of which may help decipher the etiology.

We analysed various patients whose MRI imaging revealed corpus callosum lesions. The part of the corpus callosum involved, the etiological predilection to the parts of corpus callosum, the etiology based on the part involved, and the clinical presentation was noted.

Splenium was the most common site of involvement in corpus callosum. The etiological description to various parts of corpus callosum is depicted with pictorial correlation