好色先生

好色先生

Explore the latest content from across our publications
Join The AAN

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

Post Stroke Delirium Does Not Predict Poor Cognitive Outcome at Discharge in Patients with Acute Ischemic Stroke
Cerebrovascular Disease and Interventional Neurology
P8 - Poster Session 8 (11:45 AM-12:45 PM)
13-004
N/A

Post stroke delirium (PSD) is a frequent complication of acute ischemic stroke (AIS). Stroke patients who experience delirium have worse functional outcomes than those who do not. In this study, we aim to evaluate the natural history of PSD in AIS patients and their cognitive and functional outcomes at discharge.
Between Sept 2019 and June 2021, patients diagnosed with AIS, within 48 hours of stroke onset were prospectively evaluated for delirium using the Confusion Assessment Method (CAM)-ICU daily for the first 8 days of their hospital stay. Patients with expected mortality within the first month at time of admission or with severe aphasia unable to follow commands were excluded. Prior cognitive decline was assessed using the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), and the telephone Montreal Cognitive Assessment (tMoCA) was used to evaluate current cognitive status. tMoCA scores <19 were defined as having cognitive impairment (CI).
Of patients screened for PSD, 59 consented to receive cognitive testing at discharge. PSD was present in 49.7% of our overall screening population, and in 32.8% of patients who consented for cognitive testing. There were no differences in age, gender, or NIHSS among patients with and without delirium. There was no difference in the presence of premorbid cognitive decline among patients with and without delirium (p=1.00). Patients with PSD did not have statistically significant difference in CI at discharge (p=0.11) but numerically, more patients with delirium had CI at discharge than those without delirium (74% vs 54%).
In a cohort of AIS patients without significant expected mortality on admission, delirium was not associated with worse cognitive impairment at discharge. Additional research is needed to assess how discharge cognitive impairment translates into long-term cognitive and functional outcomes.
Authors/Disclosures
Sahar S. Anjum, MS (UTHealth)
PRESENTER 		Miss Anjum has nothing to disclose.
No disclosure on file
Bethany Williams, PhD (UTHealth At Houston) Dr. Williams has received research support from UTHealth at Houston.
Alicia Zha, MD (The Ohio State University Wexner Medical Center) The institution of Dr. Zha has received research support from 好色先生. The institution of Dr. Zha has received research support from American Board of Psychiatry and Neurology.