Abstract Details

Title Admission rates, time-trends, risk factors and outcomes of ischaemic and haemorrhagic stroke in German nationwide data

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P8 - Poster Session 8 (11:45 AM-12:45 PM)

Poster/Presentation
Number 13-006

Objective Given the major changes to acute stroke treatments and guidelines in the last decade, we aimed to investigate the stroke admission rates, time-trends, risk factors, and outcomes during the period of 2014-2019 using German nationwide data.

Background Several landmark trials concerning acute ischemic and hemorrhagic stroke treatments were published during the last decade including trials for mechanical thrombectomy, an extended time window for thrombolysis, and intensive blood pressure lowering for intracerebral haemorrhage. In this changing landscape, we describe nationwide “real-world” data on time trends in stroke hospitalization admission rates, risk factor profiles and predictors of in-hospital mortality after stroke hospitalization.

Design/Methods

We obtained and analyzed data from the Research Data Centers of the Federal Statistical Office and the Statistical Offices of the Laender (Statistisches Bundesamt, DESTATIS; https://www.destatis.de) for the years 2014-2019 with respect to in-hospital outcomes and time trends related to acute stroke patients.

Results Between 2014 and 2019, overall stroke hospitalization rates initially increased from 306,425 in 2014 to peak at 318,849 in 2017 before falling to again to 312,692 in 2019, whereas percentage stroke hospitalizations that resulted in death remained stable during this period at 8.5% in 2014 and 8.6% in 2019. In a multivariate model of 1,882,930 patients, the strongest predictors of in-hospital stroke mortality were haemorrhagic subtype (Adjusted OR [aOR] = 3.06, 95% CI 3.02-3.10; p<0.001), cancer (aOR = 2.11, 2.06-2.16; p<0.001), congestive heart failure (aOR = 1.70, 1.67-1.73; p<0.001), and peripheral vascular disease (aOR =1.76, 1.67-1.84; p<0.001).

Conclusions Despite recent advances in acute stroke care over the last decade, the percentage of stroke hospitalizations resulting in death remained unchanged. Further research is needed to determine how best to optimise stroke care pathways for multimorbid patients.

Authors/Disclosures
Dearbhla Kelly, MD (Wolfson Centre for the Prevention of Stroke and Dementia) PRESENTER	Dr. Kelly has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file

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