Abstract Details

Title Mini-Child Tourette Syndrome Impairment Scale Scores in Functional versus Primary Tic Disorders

Topic Movement Disorders

Presentation(s) P17 - Poster Session 17 (11:45 AM-12:45 PM)

Poster/Presentation
Number 5-002

Objective

To investigate differences in Mini-Child Tourette Syndrome Impairment Scale (Mini-CTIM) scores rated by parents and patients with functional tics versus primary tic disorders.

Background The mini-CTIM is a validated clinical tool for assessing tic and non-tic related impairment in children with tic disorders. Recently, in the context of the COVID-19 pandemic, there has been a dramatic increase in the number of patients presenting with new onset functional tic-like behaviors. There is limited clinical data on how quality of life is impaired in these patients.

Design/Methods We reviewed parent and patient mini-CTIM scores in patients with a final diagnosis of functional tics for new patient encounters between 3/24/2021 and 6/29/2021, identifying 18 patients. Mini-CTIM scores are completed by both the parent and patient as part of a standard pre-visit intake in our Tourette’s clinics. The mini-CTIM has two parts: motor/vocal tic impairment(mini-CTIM motor/vocal) and impairment related to ADHD/OCD/anxiety/rages/other(mini-CTIM other). The maximum score of each part is 42; higher scores suggest more impairment. Twenty patients with initial visits for primary tic disorders, matched for age and sex, were randomly selected during the same corresponding time period for comparison. Parametric(unpaired t-test) and non-parametric(Wilcoxon Rank Sum Test) statistical analysis were performed when appropriate.

Results

The average age of patients with functional tics was 15.8 years at initial visit and 94% were female. Average(median) mini-CTIM tic scores in functional tic disorders families were: patient 6.5(5.5); parent 6.9(5.0). In primary tic disorder families, scores were: patient 7.6(5.0); parent 7.4(5.0).

Mini-CTIM other scores in functional tic disorders families were: patient 10.1(9.5); parent 11.4(10.0). In primary tic disorder families, scores were: patient 10.7(13.0) and parent 10.3(10.0).

No differences in mini-CTIM measures rose to the level of statistical significance.

Conclusions Despite dramatic symptoms, impairment ratings at home, school and social environment do not appear to be elevated compared with primary tic disorders.

Authors/Disclosures
Travis Larsh, MD (Cincinnati Children's Hospital Medical Center) PRESENTER	Dr. Larsh has nothing to disclose.
Steve Wu, MD (Cincinnati Children'S Hospital Medical Center)	The institution of Dr. Wu has received research support from Tourette Association of America.
Donald Gilbert, MD, FAAN (Cincinnati Children's Hospital Med. Ctr.)	Dr. Gilbert has received personal compensation in the range of $500-$4,999 for serving as a Consultant for PTC Therapeutics. Dr. Gilbert has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Illumina. Dr. Gilbert has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Emalex Biosciences. The institution of Dr. Gilbert has received research support from NIMH. The institution of Dr. Gilbert has received research support from Emalex Biosciences. The institution of Dr. Gilbert has received research support from PTC Therapeutics. The institution of Dr. Gilbert has received research support from Department of Defense. The institution of Dr. Gilbert has received research support from Quince Therapeutics. Dr. Gilbert has received publishing royalties from a publication relating to health care. Dr. Gilbert has received publishing royalties from a publication relating to health care. Dr. Gilbert has received personal compensation in the range of $500-$4,999 for serving as a Medical Second Opinion Expert with Teldoc/Advanced Medical. Dr. Gilbert has received personal compensation in the range of $10,000-$49,999 for serving as a Medical Expert with Department of Health and Human Services/Vaccine Injury Compensation Program.

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