Abstract Details

Title Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Hazardous Waste Sites? A Statewide Planning and Research Cooperative System (SPARCS) Study 1998-2014

Topic General Neurology

Presentation(s) P4 - Poster Session 4 (8:00 AM-9:00 AM)

Poster/Presentation
Number 6-005

Objective To investigate if there is an increase in the rate of CIDP among patients indirectly exposed to higher levels of hazardous waste.

Background Residence near hazardous waste sites has been previously associated with an increased risk of cardiovascular diseases and cancer.

Design/Methods CIDP patients were retrieved from the Statewide Planning and Research Cooperative System (SPARCS) database from 1998-2014 using the ICD9 code of CIDP (357.81) as the primary diagnosis. Registry of designated hazardous waste sites (POP) was retrieved from the New York State Department. POPs were classified from POP1-3 with POP3 having the highest number of hazardous sites. We compared the prevalence of CIDP among groups with different level of exposure to POP sites according to the number of nearby hazardous waste sites.

Results We identified 2,850 CIDP patients in the SPARCS database. 1,435 (50.35%) CIDP patients resided near at least one POP. In NY state, 44.32% of the total average resident population resided near at least one POP. The prevalence of CIDP is not significantly higher living near a POP site compared to NY state population living near Non-POP areas (1.395 per 100,000 vs 1.095 per 100,000, p=0.0614>0.05). The prevalence of CIDP was not significantly increased as the severity of exposure increased compared to the NY state population (Non-POP 1.095 per 100,000; POP1 1.407 per 100,000; POP2 0.926 per 100,000; POP3 0.633 per 100,000 p<0.0001). The gender, race, ethnicity, and age of CIDP patients in POPs was not significantly different compared to non-POP.

Conclusions Although the prevalence of CIDP was higher in areas with an increased number of hazardous sites and was the highest among POP1, it was not significant and was not correlated with the severity of exposure. Work is in progress with subgroup analysis to identify if there is an increased risk of CIDP after environmental pollutant exposure.

Authors/Disclosures
Mustafa Jaffry PRESENTER	Mr. Jaffry has nothing to disclose.
Yueqing Zhang (Rutgers University)	Ms. Zhang has nothing to disclose.
Sanjila Islam, MD (Rutgers New Jersey Medical School)	Dr. Islam has nothing to disclose.
Kranthi K. Mandava	Mr. Mandava has nothing to disclose.
Kazim Jaffry	Mr. Jaffry has nothing to disclose.
Nizar Souayah, MD, FAAN (NJMS)	Dr. Souayah has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Takeda. Dr. Souayah has received publishing royalties from a publication relating to health care.

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