Abstract Details

Title Association between Sarcopenia and Diabetic Peripheral Neuropathy: A Systematic Review and Meta-Analysis.

Topic Neuromuscular and Clinical Neurophysiology (EMG)

Presentation(s) P9 - Poster Session 9 (5:30 PM-6:30 PM)

Poster/Presentation
Number 11-010

Objective Our systemic review and meta-analysis identified the relationship between diabetic peripheral neuropathy (DPN) and sarcopenia by investigating all eligible studies and summarizing their results.

Background DPN, a common complication of diabetes mellitus, typically involves either somatic or autonomic nervous system and may play an important role in muscle structure and function. Prior studies have reported an association between DPN and sarcopenia, although their relationship was inconsistent.

Design/Methods A study was performed by using MEDLINE and EMBASE database from inception to January 1^st, 2021, to identify all cross-sectional studies that investigated the association between the presence DPN and sarcopenia among diabetic patients. Data from eligible studies, including point estimates and standard errors, were analyzed using the generic inverse variance method by DerSimonian and Laird.

Results Of 3,007 retrieved articles, four studies met the inclusion criteria and were included in the meta-analysis. The pooled analysis found a significant association between sarcopenia and DPN with the pooled odds ratio of 1.58 (95% CI, 1.22 – 2.05; I² 0%).

Conclusions The current study found a significant association between DPN and sarcopenia among diabetic patients.

Authors/Disclosures
Thapat Wannarong, MD PRESENTER	Dr. Wannarong has nothing to disclose.
Persen Sukpornchairak, MD (University Hospitals Cleveland Medical Center)	Dr. Sukpornchairak has nothing to disclose.
Christopher D. Geiger, MD, FAAN (University Hospitals-Cleveland Medical Center)	Dr. Geiger has nothing to disclose.
	No disclosure on file

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