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Abstract Details

Does Perfusion Computed Tomography Abnormalities in Patients with Transient Ischemic Attack Predict Subsequent Ischemic Stroke and Cardiovascular Event?
Cerebrovascular Disease and Interventional Neurology
P1 - Poster Session 1 (9:00 AM-5:00 PM)
083

To determine if computed tomography (CT) perfusion (CTP) abnormalities in patients with transient ischemic attacks (TIA) are associated with development of ischemic strokes or adverse cardiovascular events within 24 months.
To determine if computed tomography (CT) perfusion (CTP) abnormalities in patients with transient ischemic attacks (TIA) are associated with development of ischemic strokes or adverse cardiovascular events within 24 months.
Patients with a diagnosis of TIA who underwent CTP within 24 hours of symptom onset as part of the stroke/TIA imaging protocol were analysed. Abnormality was defined as an area of well demarcated mean transit time delay and/or cerebral blood flow reduction corresponding to an arterial territory as identified by an independent neuroradiologist. The patients were followed for at least 3 months and up to 24 months to identify occurrence of ischemic stroke and cardiovascular events (myocardial infarction or ischemia).
A total of 78 patients (mean age 67.60 +/- 15.1 ; 48 were men) with a diagnosis of TIA. A total of 17 patients (22%) had documented CTP abnormalities. Patients with CTP abnormalities were older and more likely to be men. There was no difference in the rates of ischemic stroke (5.9 %  vs  3.3 %), or   cardiovascular events (0% versus 1.6 %) when patients with CTP abnormalities were compared to those with normal CTP.  

In patients with TIA, an abnormal CTP does not predict the occurrence of new ischemic stroke or cardiovascular events during follow up.

Authors/Disclosures
Aisha Abdulrazaq, MBBS (Mayo Clinic)
PRESENTER 		Dr. Abdulrazaq has nothing to disclose.
Muhammad F. Ishfaq, MD Dr. Ishfaq has nothing to disclose.
Hamza I. Maqsood, MD (Dept of Neurology) Dr. Qureshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AstraZeneca.