To study the effect of anemia and cerebral collaterals on the functional outcome in subjects suffering from acute ischemic stroke at the end of one month 

Large Vessel Occlusion acute ischemic stroke cases from a tertiary care hospital between January 2016 and December 2020 were included in this study. Hemoglobin level at hospital admission, Collateral score in CTA and other demographic factors during hospitalization were noted. A multivariable logistic regression model was used to determine risk-adjusted odds of unfavorable outcome in one month, defined as a modified Rankin Score of > 2.

A total of 135 LVO patients were included in the study of which 38 were females. The prevalence of anemia on admission was 22.2 %. The proportion of anemic subjects (25.8%) was higher in the poor outcome group than the good outcome group. Baseline collateral graded using MAAS score, NIHSS and ASPECT score were significantly lower in the poor outcome group as compared to the good outcome group. In Hemoglobin subgroups, anemia independently predicted poor outcome OR 4.95 (1.24–19.8). One unit drop in ASPECT score, MASS Score, and one-unit increase in NIHSS independently increased the risk of poor outcome by an OR 0.73(0.6-0.9), 0.21(0.1-0.4) and 1.1(1-1.2) respectively.

Admission Anemia status, Collateral score in baseline CT Angiography, CT ASPECTS score and NIHSS were independently associated with poor clinical outcome stroke patients.