Abstract Details

Title Re-evaluating Risk Factors, Incidence, and Outcome of Aneurysmal and Non-aneurysmal Subarachnoid Hemorrhage

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P1 - Poster Session 1 (9:00 AM-5:00 PM)

Poster/Presentation
Number 120

Objective In the present study, we aimed to prospectively evaluate SAH and its subcategories incidences and related clinical features in central Iran.

Background Subarachnoid hemorrhage (SAH) is one of the life-threatening types of stroke throughout the world. SAH can be classified into two main categories, aneurysmal (aSAH) and non-aneurysmal SAH (naSAH).

Design/Methods All SAH patients diagnosed between 2016-2020 were included in Isfahan SAH Registry (ISR) program. Demographic, clinical characteristics, incidence rates based on the age categories, as well as laboratory and imaging findings were collected and compared between aSAH and naSAH groups. Complications during hospital stay and outcomes were also analyzed. Binary logistic regression analysis was performed to investigate the predictors of aSAH versus naSAH. Kaplan-Meier curves and Cox regression were used to evaluate survival.

Results A total of 461 SAH patients were included through ISR. The SAH annual incidence rate was 3.11 per 100,000 person-years. aSAH had a higher incidence rate than naSAH (2.08/100,000 versus 0.9/100,00 person-years). In-hospital mortality was 18.2% with no significant difference between aSAH and naSAH subgroups. Hypertension (p=0.003) and smoking (p=0.03) were significantly associated with aSAH, whereas DM (p<0.001) was more associated with naSAH. Cox regression analysis showed higher hazard ratios for reduced in-hospital survival for those with altered mental status, Glasgow coma scale ≤13, rebleeding, and seizures.

Conclusions This study provided an updated estimation of SAH and its subgroups incidences in central Iran. Different risk factors might be associated with aSAH and naSAH.

Authors/Disclosures
Jorge D. Kim, MD (The Children's Hospital of Philadelphia (CHOP)) PRESENTER	Dr. Kim has nothing to disclose.
Alireza Zandifar, MD (The Children's Hospital of Philadelphia, Roberts Center for Pediatric Research)	Dr. Zandifar has nothing to disclose.
	No disclosure on file
Luis Octavio Tierradentro Garcia, MD (Children's Hospital of Philadelphia)	Dr. Tierradentro Garcia has nothing to disclose.
	No disclosure on file
Arastoo Vossough, MD (University of Pennsylvania - Children'S Hospital of Philadelphia)	Dr. Vossough has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Syneos Health. Dr. Vossough has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for DeepSight. Dr. Vossough has received publishing royalties from a publication relating to health care.
	No disclosure on file

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