Abstract Details

Title Prescription Patterns of Triptans in the Treatment of Migraine

Topic Headache

Presentation(s) P1 - Poster Session 1 (9:00 AM-5:00 PM)

Poster/Presentation
Number 201

Objective This work aims to evaluate the existence of statistically significant geospatial clusters in the use of triptans for treatment of migraine and identify factors that underlie cluster formation.

Background Triptans, which act on 5-HT 1b/1d receptors, are an effective treatment for acute migraine headaches.

Design/Methods This study utilizes publicly available Medicare data from 2014 to 2019 to assess the prescription patterns of triptans in the United States. Data analysis was performed in Python; GeoDa was used for geospatial visualization. Moran’s I statistic was calculated and plotted for 2899 counties. Factorial ANOVA was performed to identify significant variables in cluster formation. Separate analyses were performed for migraine diagnoses, triptan prescriptions, and triptan prescriptions specifically by neurologists.

Results There were statistically significant clusters in the diagnosis of migraines: A continuous High-High cluster was found in the Appalachian region, extending into the South and portions of the Midwest. Low-Low clustering was prominent in the Great Plains with smaller scattered clusters on the East Coast.
Assessing overall triptan prescriptions, one prominent High-High cluster was found in the Southern states of Tennessee, Alabama, and Georgia. There were several prominent Low-Low clusters scattered throughout the United States along the East Coast, Great Plains, and Gulf Coast.
Triptan prescription clusters were found to be significantly associated with gender, race, employment status, education, household income, and tobacco utilization (p < 0.001).
Isolating the percentage of triptans prescribed by neurologists demonstrated prominent High-High clustering along the East Coast and Florida; Low-Low clustering was noted in the Great Plains.

Conclusions Geospatial analysis reveals a surprising clustering effect in the diagnosis of migraine in Medicare members. Additionally, the overall prescription rates of triptans and the percentage of triptans prescribed by neurologists demonstrate significant clustering as well. Factorial ANOVA reveals the contributions of race, geography, and socioeconomic status in the formation of these clusters.

Authors/Disclosures
Ariana Barreau, MD (Home) PRESENTER	Miss Barreau has received personal compensation for serving as an employee of Cala Health. Miss Barreau has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cala Health.
	No disclosure on file
	No disclosure on file
	No disclosure on file

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