Abstract Details

Title Associations of small vessel disease and seizures among hospitalized stroke patients

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P12 - Poster Session 12 (5:30 PM-6:30 PM)

Poster/Presentation
Number 9-007

Objective To evaluate the association of white matter disease and cerebral microbleeds with seizures among hospitalized patients with ischemic stroke.

Background Small vessel diseases are frequent in ischemic stroke, yet unlike hemorrhagic strokes, their association with seizures has not been well characterized.

Design/Methods Retrospective cohort of hospitalized patients with anterior circulation ischemic stroke. The association of White matter disease and cerebral microbleeds with seizures was assessed using a logistic regression model.

Results

Of 381 patients, 17 developed seizures. Compared with patients without CMBs, those with CMBs had four-fold higher odds of seizures (adjusted OR: 4.36, 95% 1.23-15.34, p=0.02). White matter disease burden was not associated with seizures.

Conclusions In this cohort of hospitalized patients with anterior circulation ischemic stroke, the presence of 4 or more CMBs increased the risk of seizures. The long-term risk of seizures associated with CMBs and other markers of small vessel disease is warranted.

Authors/Disclosures
Alain Z. Lekoubou Looti, MD (Penn StateHealth, Hershey Medical Center) PRESENTER	Dr. Lekoubou Looti has nothing to disclose.
	No disclosure on file
	No disclosure on file
Kunal Debroy, MD (Montefiore Medical Center)	Mr. Debroy has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Vivek Satyasi, MD	Dr. Satyasi has nothing to disclose.
Leonardo F. Bonilha, MD (University of South Carolina)	Dr. Bonilha has nothing to disclose.
	No disclosure on file

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