Abstract Details

Title Characteristics of Patients With Lennox-Gastaut Syndrome and Predictors for a Longer Stay Following Hospitalization

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P3 - Poster Session 3 (5:30 PM-6:30 PM)

Poster/Presentation
Number 9-011

Objective To investigate characteristics of Lennox-Gastaut syndrome (LGS) patients and factors that influence the length of stay (LOS).

Background LGS is a rare form of severe epileptic encephalopathy, and there is a paucity of data on these patients.

Design/Methods The 2019 National Inpatient Sample(NIS) from HCUP, AHRQ, and partners was used first to find cases of LGS with a principal diagnosis. Various patient characteristics were also studied. The mean LOS was explored, and variables that could lead to a longer than mean LOS were also probed via regression models.

Results We found 3210 patients with a principal diagnosis of LGS. The mean LOS was 4.17 days. Patients with LGS were predominantly males (54.4%), Whites (51.4%), and dependent on Medicaid (52.5%). Only 1.6% had diabetes, 4.7% had hypertension, 2.8% reported a diagnosis of depression, and 4.0% were obese. 15.9% of cases were admitted on the weekend. The overall mean age of all patients with LGS was 17.12 years. After adjusting for several factors, several variables were observed that could predispose to a longer hospital stay (LOS≥5 days), such as ages ≥60years (aOR 2.339, p=0.014) and 20-39 years (aOR1.368, p=0.004) (compared to patients of ages 0-19 years), diabetes (aOR 2.012, p=0.026), and hypertension (aOR 2.264, p<0.01), while LGS patients covered by private insurances (aOR 0.614, p=0.007) showed a lower risk relative to Medicare beneficiaries. No statistically significant risks were seen for sex, race, depression, obesity, and admission on the weekend. Finally, patients with a longer LOS were older (mean age of 20.10 years) compared to those with LOS <5 (mean age of 16.09 years).

Conclusions Our study provides an up-to-date perspective on various patient characteristics with LGS and factors that can cause a longer hospitalization, including different age groups, diabetes, and hypertension. Further studies addressing these differences can help optimize the care of these patients.

Authors/Disclosures
Shaheen Sombans, MBBS (Fernandez Foundation) PRESENTER	Dr. Sombans has nothing to disclose.
Sailaja Sanikommu, MBBS (V.N.M Hopsital)	Dr. Sanikommu has nothing to disclose.
Kamleshun Ramphul	Kamleshun Ramphul has nothing to disclose.
Renuka Verma (KIRK KERKORIAN SCHOOL OF MEDICINE)	Renuka Verma has nothing to disclose.
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