Abstract Details

Title Chiari I malformation: Clinical Characteristics, Symptoms, and Presentations.

Topic General Neurology

Presentation(s) P10 - Poster Session 10 (8:00 AM-9:00 AM)

Poster/Presentation
Number 12-005

Objective We aim to conduct this retrospective study to compare surgery and conservative treatment’s demographics, clinical presentations, and interventions for CM-1 patients in a tertiary hospital in Jordan.

Background Chiari malformation type 1 (CM-1) is a congenital anomaly associated with herniation of tonsillar pillars due to abnormality in hindbrain. Standard practice in treatment of (CM-1) is surgical decompression or conservative observation.

Design/Methods We reviewed our hospital’s patients’ clinical records, Brain MRI, and surgical assessment notes for CM-1 patients who presented to our hospital for the period between 2000 to 2022.

Results We identified 37 patients with (mean age) of (26.5 +/- 19.77) years old and a female predominance n=21 (56.75%). Most patients were incidentally diagnosed or presented without symptoms n=22 (59.45%). Out of the 37 patients identified n=7 (18.9%) underwent surgery while n=30 (81.1%) were treated conservatively. Patients who underwent surgery were older in age compared to those who did not with a (mean age +/- S.D.) of (33.00 years +/- 16.5) and (25.03 +/- 20.40), respectively (p=0.08). Surgery was associated with worsening of symptoms compared to observation 57.14% vs 13.33% (p=0.01). Females were as likely to undergo surgery compared to males 19.04% vs 18.75% (p=0.98). Headache was the initial presentation in n=15 (40.50%) of the patients, other common presentations include: cranial nerve deficits n=20 (54.05%), neck and back pain in n=8 (21.62%), and gait abnormalities n=4 (10.81%).

Conclusions Chiari malformation type 1 is a medical condition with a wide array of clinical presentations that is hard to diagnose. Optimum treatment for CM-1 and its association with symptoms alleviation needs further investigation.

Authors/Disclosures
Yazan S. Al-Zamer (Jordan University of Science and Technology) PRESENTER	Mr. Al-Zamer has nothing to disclose.
Samah K. Aburahma, MD (Jordan University S & TFaculty of Medicine)	Dr. Aburahma has nothing to disclose.
	No disclosure on file
Ethar Hazaimeh, MD	Dr. Hazaimeh has nothing to disclose.
Omar Jbarah (Jordan University of Science and Technology)	Omar Jbarah has nothing to disclose.

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