A total of 3319 patients were identified. Of these 196 TIA patients were excluded from the analysis. Mean age was 67.8 ± 15.27 years. Readmission rate was 9.5% for the whole cohort (ischemic stroke 7.7% and hemorrhagic stroke 14%). Readmitted patients had a high LACE+ score (≥ 60; 73%), low aNIHSS (0-5; 50%), were smokers (61%) and did not have an established PCP (94%) at the time of index admission. Readmitted patients were also less likely to have received thrombolysis (88%) or thrombectomy (80%) during index admission. Logistic regression incorporating LACE+, aNIHSS and stroke type (hemorrhage) were mildly predictive of 30-day unplanned readmission (Model A; c-stat 0.60). Addition of smoking status, alcohol status, primary care physician status, thrombolysis and thrombectomy use slightly improved the predictive ability of the model (Model B; c-stat 0.62).

LACE+ is marginally predictive of 30-day unplanned readmission after stroke. Better scores incorporating socioeconomic, neurological and cerebrovascular variables are needed to predict readmission after stroke.