The Philippine CORONA Study is a multicenter, retrospective, cohort study of 10,881 COVID-19 admissions between February and December 2020.

Subgroup analysis was done on clinical outcomes of mortality, respiratory failure, duration of ventilator dependence (DVD), intensive care unit (ICU) admission, length of ICU stay (LICUS), and length of hospital stay (LHS) among older persons and persons with dementia.

The adjusted hazard ratios (aHRs) for mortality among the mild and severe cases were significantly higher by 3.93, 95% CI [2.81, 5.50] and by 1.81, 95% CI [1.43, 2.93], respectively, in older persons compared to younger adults. The aHRs for respiratory failure in older persons were increased by 2.65, 95% CI [1.92, 3.68] and by 1.27, 95% CI [1.01, 1.59] among the mild and severe cases, respectively. The aHR for ICU admission in older persons was higher by 1.95, 95% CI [1.47, 2.59] among the mild cases. The aHRs for mortality and ICU admission in persons with dementia were higher by 7.25, 95% CI [2.67, 19.68] and by 4.37, 95% CI [1.08, 17.63], respectively, compared to those without dementia.

Older age and dementia significantly increased the risk of mortality, respiratory failure, and ICU admission among COVID-19 patients.