We included 105 patients with confirmed GBS diagnoses. The predominant variant was acute inflammatory demyelinating polyneuropathy (n = 40, 38.1%). The median time to onset of motor recovery was 13 days, while the median hospital stay was 15 days. The difference in outcomes of patients in the IVIg (n = 44) and TPE (n = 24) groups (walking with aid/GBS-disability scores/ventilator dependency at 1 month, duration dependent on the ventilator, intensive care unit stay, and hospital stay) were not statistically significant, except for mild disability at 1 month (p = 0.009). Pneumonia (crude odds ratio (OR) 7.85, 95% CI 2.89–21.33, p < 0.001; adjusted OR 5.65, 95% CI 1.59– 20.05, p = 0.007), urinary tract infection (crude OR 6.5, 95% CI 1.39–30.47, p = 0.008; adjusted OR 15.62, 95% CI 1.80–135.82, p = 0.013), and dysautonomia (crude OR 3.60, 95% CI 1.31–9.91, p = 0.01) were significantly related to a prolonged hospital stay. Considering only the treatment groups, the hazard ratio (HR) for late onset of motor recovery comparing IVIg and TPE was 0.75 (95% CI 0.31–1.85, p = 0.533) which was not not statistically significant; after adjusting for age and sex, the HR remained insignificant (0.69, 95% CI 0.27–1.74, p = 0.429).