好色先生

好色先生

Explore the latest content from across our publications
Join The AAN

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

A History of Abuse is Associated with More Severe Migraine- and Pain-Related Disability: Results from the American Registry of Migraine Research (ARMR)
Headache
P11 - Poster Session 11 (11:45 AM-12:45 PM)
2-009
This cross-sectional, observational study of a clinic-based migraine population uses validated measures to elucidate migraine-specific and migraine-related burden among patients with a history of abuse.
Prior studies have established an association between a history of abuse and more severe migraine presentation. 
741 adult patients with migraine from ARMR self-reported their history of emotional, physical, and/or sexual abuse and completed questionnaires: Migraine Disability Assessment (MIDAS), Subjective Cognitive Impairment Scale for Migraine Attacks (Mig-SCog), Work Productivity and Activity Impairment (WPAI), PROMIS Pain Interference (PROMIS-PI), Patient Health Questionnaire-2 (PHQ-2), Generalized Anxiety Disorder-7 (GAD-7), and sociodemographics questionnaire. Differences in questionnaire scores between patients with and without a history of abuse were determined. A series of adjusted regression models qualified this relationship. A parallel mediation analysis evaluated the effects attributable to depression and anxiety.
 
36.4% (n=270) of participants reported a history of abuse. Patients with a history of abuse reported significantly greater headache frequency (19.7 days versus 18.2 days per month, p=0.037). The group with a history of abuse was significantly more female (93% versus 86%, p=0.002), achieved a lower education level (p=0.002), were more likely to be divorced, separated, or widowed (p=0.002), were more likely to be disabled from working (p<0.001), and had a lower household income (p<0.001). After controlling for patient age, sex, years lived with headache, headache frequency, and sociodemographic characteristics, a history of abuse was significantly associated with more-severe scores on every migraine-related disability measure evaluated. Though an independent effect of abuse on more-severe migraine disability persisted, psychiatric comorbidity mediated these associations, and the effect of depression was generally greater than that of anxiety.
A history of abuse is associated with greater migraine-related disability and migraine disease burden. Although the relationship between a history of abuse and migraine-related disability and burden is mediated by anxiety and depression, an independent effect remains.
Authors/Disclosures
Meesha Trivedi (Mayo Clinic AZ)
PRESENTER 		The institution of Ms. Trivedi has received research support from 好色先生.
Gina Dumkrieger, PhD (Mayo Clinic) Gina Dumkrieger has received personal compensation for serving as an employee of Mayo Clinic. The institution of Gina Dumkrieger has received research support from NIH. The institution of Gina Dumkrieger has received research support from DOD. The institution of Gina Dumkrieger has received research support from AMGEN.
Catherine D. Chong, PhD, FAAN Dr. Chong has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for HCOP.
Todd J. Schwedt, MD, FAAN (Mayo Clinic) Dr. Schwedt has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Eli Lilly. Dr. Schwedt has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Lundbeck. Dr. Schwedt has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Abbvie. Dr. Schwedt has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Linpharma. Dr. Schwedt has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Theranica. Dr. Schwedt has received personal compensation in the range of $0-$499 for serving as a Consultant for Amgen. Dr. Schwedt has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scilex. Dr. Schwedt has stock in Aural Analytics. Dr. Schwedt has stock in Nocira. Dr. Schwedt has stock in Allevalux. The institution of Dr. Schwedt has received research support from National Institutes of Health. The institution of Dr. Schwedt has received research support from United States Department of Defense. The institution of Dr. Schwedt has received research support from Patient Centered Outcomes Research Institute. The institution of Dr. Schwedt has received research support from SPARK Neuro. The institution of Dr. Schwedt has received research support from Henry Jackson Foundation. The institution of Dr. Schwedt has received research support from Pfizer. The institution of Dr. Schwedt has received research support from National Headache Foundation. The institution of Dr. Schwedt has received research support from American Heart Association. Dr. Schwedt has received intellectual property interests from a discovery or technology relating to health care. Dr. Schwedt has received intellectual property interests from a discovery or technology relating to health care. Dr. Schwedt has received intellectual property interests from a discovery or technology relating to health care. Dr. Schwedt has received intellectual property interests from a discovery or technology relating to health care. Dr. Schwedt has received publishing royalties from a publication relating to health care.