Abstract Details

Title Evaluation of Sleep Parameters with Polysomnography and Multiple Sleep Latency Test in Cirrhotic Patients with Daytime Sleepiness

Topic Sleep

Presentation(s) P1 - Poster Session 1 (8:00 AM-9:00 AM)

Poster/Presentation
Number 11-001

Objective The purpose of this study is to examine sleep parameters of cirrhosis patients who
have daytime sleepiness and evaluate their correlation in terms of minimal hepatic encephalopathy (MHE).

Background Thirty cirrhosis patients were included in our study who were 18-75 years old, followed up in Marmara University Medical Faculty Hospital between December 2021-March 2022, and had Epworth sleepiness scale (ESS) ≥ 9. PSG data of 15 age-matched patients assigned as the control group, and cirrhosis patients were compared with control group.

Design/Methods Cirrhosis patients who have excessive daytime sleepiness (EDS) were classified as A and B in accordance with Child-Pugh score and they were evaluated with MSLT in the morning following one night PSG examination. At the same time, each patient was divided into 2 groups in terms of MHE by applying a PHES test battery.

Results The mean age of cases were 57,63±10,07 (min:36- max:72) years and 17 of 30 patients (56,7%) were male. It was found that 70% cryptogenic, 20% HBV, 6.7% HCV, and 3.3% was developed on the background of alcohol etiology. The mean ESS was 12,17±3,10. There was a significant decrease in N2 (p<0,007) and increase in N3 stage (p<0,002) in cirrhosis patients. Total sleep time (TST) and sleep efficiency (SE%) were significantly lower in cirrhosis patients than healthy population ( p<0,015 and p<0,030 respectively). Patients fell asleep at 2 or more naps (97%) and 48.3% had a sleep latency of 8 or less (p<0.007). SOREMs were observed in 17% of the patients.

Conclusions EDS has objectively demonstrated with MSLT in our study, there was no difference in cirrhosis stages and MHE patients. It is believed that EDS may be a predictor for MHE patients and that EDS is the complaint that occurs earlier than the development of overt HE.

Authors/Disclosures
Kadriye Agan PRESENTER	Kadriye Agan has nothing to disclose.
Humay Ismayilzada III, MD (Atasehir Acibadem Hospital)	Mr. Ismayilzada has nothing to disclose.
Gulin Sunter (Marmara University)	No disclosure on file
	No disclosure on file

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