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Abstract Details

An Interprofessional Team for Disease Modifying Therapy in Alzheimer’s Disease Implementation
Aging, Dementia, and Behavioral Neurology
P5 - Poster Session 5 (5:30 PM-6:30 PM)
9-018

Lecanemab and other new amyloid-targeting immunotherapies for Alzheimer's disease show great promise but, may also pose significant risk for patients.  
To facilitate the implementation and monitoring of lecanemab infusions at a tertiary medical center, we convened an interprofessional team.
The team created resources including patient handouts and medical documentation templates as well as systems and processes that are likely to be useful to other clinical care settings and centers. It is our intent to widely share resources and processes developed. 
We found that that forming an interdisciplinary team comprising of behavioral neurologists, geriatricians, pharmacists, infusion nurses, neuroradiologists, and trainees is instrumental in initiating lecanemab infusions at a tertiary medical center. This team structure and process is also important in ongoing administration and monitoring of patients on lecanemab. 
The approach we have outlined may be adaptable and can be used across the medical system. Depending on each center’s infrastructure, roles might be filled by other healthcare professionals such as nurses, nurse practitioners, or physician assistants instead of fellows/residents when necessary.
Authors/Disclosures
Katherine Turk, MD (Boston VA)
PRESENTER 		The institution of Dr. Turk has received research support from Alzheimer's Association. The institution of Dr. Turk has received research support from US Department of Veterans Affairs.
Mark D. Knobel, MD, PhD (VA Boston Medical Center) Dr. Knobel has nothing to disclose.
Alexandra Nothern (VA Boston Healthcare System) No disclosure on file
Garrett M. Friedman, MD (self) Dr. Friedman has nothing to disclose.
Hannah Noah, MD Dr. Noah has nothing to disclose.
Brendan Campbell, MD No disclosure on file
Diana Anderson No disclosure on file
Antreas Charidimou, MD, PhD MSc Dr. Charidimou has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Imperative Care. Dr. Charidimou has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier, Journal of Neurological Sciences.
Andrew Mills No disclosure on file
Vanessa Coronel (VA Boston Healthcare System) No disclosure on file
Nacha Pierre No disclosure on file
Beverly Reynolds Beverly Reynolds has nothing to disclose.
Caroline Wagner No disclosure on file
Leanne Varga (VA Boston Healthcare System) No disclosure on file
John Roefaro (VA Boston Healthcare System) No disclosure on file
Laura Triantafylidis (VA Boston Healthcare System) No disclosure on file
Andrew E. Budson, MD (VA Boston Healthcare System) Dr. Budson has received personal compensation for serving as an employee of Boston Center for Memory. Dr. Budson has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Genentech. Dr. Budson has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AbbVie. Dr. Budson has received personal compensation in the range of $50,000-$99,999 for serving on a Speakers Bureau for Eli Lilly. The institution of Dr. Budson has received research support from Department of Veterans Affairs. The institution of Dr. Budson has received research support from NIH. The institution of Dr. Budson has received research support from Bristol Myers Squibb. The institution of Dr. Budson has received research support from VoxNeuro. The institution of Dr. Budson has received research support from Eisai. Dr. Budson has received publishing royalties from a publication relating to health care. Dr. Budson has received publishing royalties from a publication relating to health care. Dr. Budson has a non-compensated relationship as a Alzheimer's Advisory Panel with Commonwealth of Massachusetts that is relevant to AAN interests or activities.