Abstract Details

Title Stroke Patients in an Alcohol Withdrawal State (SPAWS Study) - Clinical Profiles and Functional Outcomes During Hospital Stay in a Tertiary Hospital

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P1 - Poster Session 1 (8:00 AM-9:00 AM)

Poster/Presentation
Number 5-029

Objective

This study aimed to investigate the association between alcoholic withdrawal (AW) and acute stroke profiles and outcomes through a cross-sectional analysis of patients admitted to a tertiary hospital.

Background Patients who experience acute strokes are also at risk of developing a wide range of complications. When these complications coincide with acute alcohol withdrawal syndrome, they can lead to more severe events that may result in death, disability, or delayed recovery.

Design/Methods

This cross-sectional study included all adult Filipino patients diagnosed with acute ischemic, hemorrhagic stroke, and subarachnoid hemorrhage in an alcohol withdrawal state, admitted from 2018 to 2023 (n=36). Demographic and clinical data, as well as outcomes, were collected through a review of medical records.

Results Key findings revealed a male predominance (n=34, 94.44%) among patients, with the majority aged 40-59 years (n=28, 77.78%), and a significant prevalence of hemorrhagic strokes (n=30, 83.33%). Approximately (n=17, 47.22%) of individuals presented with mild alcohol withdrawal symptoms at admission, with (n=20, 55.56%) displaying an alcohol withdrawal timeline ranging from 24 hours to one week. Notably, (n=13, 36.11%) of patients were categorized as having a moderate stroke, as assessed by the NIHSS score. In terms of outcomes, (n=9, 25%) of patients demonstrated no substantial disability, contrasting with a (n=8, 22.22%) mortality rate. (n=20, 55.56%) stayed in the hospital for 1-2 weeks, with at most 1 week (n=27, 75%) of ICU stay. Substantial correlation between the severity of alcohol withdrawal (CIWA-Ar) and functional outcomes (mRS), with a p-value of 0.031, suggesting that heightened withdrawal symptomatology correlates with increased functional impairment.

Conclusions

The study revealed significant associations between age, gender, alcohol withdrawal timelines, and functional outcome. Furthermore, the correlation between mRS scores and CIWA-Ar components presents a promising predictive tool for improving patient management in this specific population, emphasizing the need for a timely intervention to optimize rehabilitation and recovery.

Authors/Disclosures
Jenielyn Nazaire, MD PRESENTER	Dr. Nazaire has nothing to disclose.
John Harold Hiyadan	No disclosure on file

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