To identify characteristics of individuals with Chronic atrial fibrillation (cAF) who underwent Endovascular thrombectomy (ET).

ET is often used for treating acute ischemic stroke (AIS), a common complication of cAF. Patient selection for ET is based on the onset and clinical symptoms, functional baseline and imaging characteristics.

Out of 50,475 patients with cAF admitted for AIS, 13.9%  underwent ET. Dyslipidemia (aOR 1.132, p<.001), obesity (aOR 1.218, p<.001), and Hispanic race (aOR 1.313, p<.001, vs. white) had higher odds of requiring ET. Age ≥ 60 (aOR 0.642, p<.001), chronic kidney disease (CKD) (aOR 0.806, p<.001), prior stroke (aOR 0.807, p<.001), diabetes mellitus (aOR 0.749, p<.001), and Black race (vs. white, aOR 0.851Q, p=0.002) showed lower odds. Drug abuse (aOR 0.884, p=0.419), alcohol abuse (aOR 1.178, p=0.078) and smoking (aOR 0.937, p=0.051), as well as cirrhosis (aOR 0.718, p=0.062), hypertension (aOR 1.011, p=0.743), peripheral vascular disease (aOR 0.97, p=0.595), female sex (vs. male, aOR 0.99, p=0.743), long-term anticoagulation (aOR 1.055, p=0.063), and weekend admissions (aOR 0.972, p=0.371), showed no statistical significance.

Obesity, dyslipidemia, and Hispanic race were associated with higher odds of undergoing ET, while age ≥ 60, CKD, prior stroke, DM, and Black race were less likely to undergo ET, probably due to associated contraindications. Exploring the relationship between these factors could help clinicians predict ET candidacy, impacting treatment options, and prognosis.