Abstract Details

Title People with Epilepsy (PWE) and Attention Deficit Hyperactive Disorder (ADHD)/Attention Deficit Disorder (ADD)

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P4 - Poster Session 4 (11:45 AM-12:45 PM)

Poster/Presentation
Number 1-001

Objective To determine the relationship between epilepsy and ADHD/ADD

Background The association between epilepsy and comorbid ADHD/ADD is still under-recognized in clinical practice, even though the well-established bidirectional connection has been noted. Studies have shown a potential relationship between focal and generalized epilepsy with ADHD/ADD.

Design/Methods Patients diagnosed with epilepsy and ADD/ADHD were included in the study population from our epilepsy database (2019-present). Patients with ADHD was analyzed from the epilepsy database using SPSS software, variables were compared using chi-square test and means of groups were compared using t-test.

Results There are 3025 patients in the epilepsy database out of which 237 had ADHD/ADD. About 48.6% were men and 51.4% were women. The mean age was 38.70±25.8 years in the PWE without ADHD/ADD while in the ADHD group the mean age was 32.65±20.15 (p-value <0.01). The mean age of onset of seizure in the ADHD group was 22.33±20.16 years vs 26.04±22.13 years in the PWE without ADHD/ADD group (p-value <0.05). Among the ADHD group 33.8% had focal epilepsy compared to 38.5% in the PWE without ADHD/ADD (p-value 0.164). There was an increased incidence of generalized epilepsy in the ADHD group compared to the control group (39% vs 31.9% p value <0.05). Furthermore, there was an increased correlation of Childhood Absence Epilepsy (CAE) in the ADHD group (21.5% vs 6.1% p-value <0.001). EEG data was available for 180 patients in the ADHD group out of which 54 showed epileptiform changes compared to 1388 in the PWE without ADHD/ADD, out of which 183 showed epileptiform changes (30% vs 13.1% p-value 0.08).

Conclusions

In this study, patients with ADHD have a higher incidence of generalized epilepsy and more specifically CAE. Our study strengthens the point that ADHD is significantly associated with childhood absence epilepsy.

Authors/Disclosures
Syed Muhammad Owais (University of Toledo) PRESENTER	Mr. Owais has nothing to disclose.
Fahham Asghar, MD (The University of Toledo)	Mr. Asghar has nothing to disclose.
Hira Pervez, MD, MBBS (University of Toledo)	Dr. Pervez has nothing to disclose.
Sidra Saleem, MD (University of Toledo)	Dr. Saleem has nothing to disclose.
Sumayya Naz, MD (ProMedica Neuroscience Center)	Dr. Naz has nothing to disclose.
Ajaz Sheikh, MD (ProMedica Neurosciences Center)	Dr. Sheikh has nothing to disclose.
Naeem Mahfooz, MD	Dr. Mahfooz has nothing to disclose.
Joyeta Razzaque, MBBS	Dr. Razzaque has nothing to disclose.
Rabia Zubair, MD	Dr. Zubair has nothing to disclose.
Bashar Saour, MD (University of Toledo)	Dr. Saour has nothing to disclose.
Anum H. Riaz, MD	Dr. Riaz has nothing to disclose.
Imran I. Ali, MD, FAAN (University of Toledo COM)	Dr. Ali has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for ABPN.

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